Results 81 to 90 of about 422,762 (346)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Erratum: Simultaneous silence organizes structured higher-order interactions in neural populations [PDF]

open access: yesScientific Reports, 2015
Activity patterns of neural population are constrained by underlying biological mechanisms. These patterns are characterized not only by individual activity rates and pairwise correlations but also by statistical dependencies among groups of neurons larger than two, known as higher-order interactions (HOIs). While HOIs are ubiquitous in neural activity,
Shimazaki, Hideaki   +4 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Bleeding Words: Louise Bourgeois' and José Leonilson's Love Images [PDF]

open access: yes, 2016
As one tries to grasp love and its images within José Leonilson's production, a multiplicity of aspects and meanings are seen that also relate to Louise Bourgeois's oeuvre in regard to the interest in human relations.
Ana Lucia, Beck, Maria, Berwanger
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Social Justice Documentary: Designing for Impact [PDF]

open access: yes, 2011
Explores current methodologies for assessing social issue documentary films by combining strategic design and evaluation of multiplatform outreach and impact, including documentaries' role in network- and field-building.
Barbara Abrash, Jessica Clark
core  

Voice and silence as immediate consequences of job insecurity

open access: yes, 2020
The purpose of this paper is to examine the weekly effects of job insecurity on employee voice and silence. Specifically, the authors argue that because employment fulfils important needs, employees’ needs are less fulfilled when they feel that their job
Kimberley Breevaart   +3 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Study of the Relationship between Organizational Identity and Organizational Silence among Employees of the University of Isfahan

open access: yesجامعه شناسی کاربردی, 2014
Introduction As a competitive advantage in organizations, identity has become significant in recent years. It is a unique quality that distinguishes one person from others and is communicated through appearance, behavior and values of the person; the ...
Ali Nasr Isfahani   +1 more
doaj  

Investigating the Role of Moral Leadership in Predicting of Job Behavior and Breaking the Organizational Silence [PDF]

open access: yesPizhūhish/hā-yi rahbarī va mudīriyyat-i āmūzishī, 2017
The purpose of this study was investigating the role of moral leadership in predicting the development of job behavior and breaking the organizational silence.
ali khaleghkhah   +2 more
doaj   +1 more source

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