Results 11 to 20 of about 5,855 (222)
A Comparison of the Diastereoisomers, Silybin A and Silybin B, on the Induction of Apoptosis in K562 cells [PDF]
Natural Product Communications, 2011 Two diastereoisomers of silybin, silybin A and silybin B, were separated from silymarin by HPLC in our previous study. The present study assessed the effects of the diastereoisomers on cell apoptosis, and compared these with their mixture, silybin, in ...
Jiyong Zhang +4 more
doaj +3 more sources
Chemo-Enzymatic Synthesis of Silybin and 2,3-Dehydrosilybin Dimers [PDF]
Molecules, 2014 Divalent or multivalent molecules often show enhanced biological activity relative to the simple monomeric units. Here we present enzymatically and chemically prepared dimers of the flavonolignans silybin and 2,3-dehydrosilybin.
Eva Vavříková +6 more
doaj +3 more sources
Enhanced Anti-Aging Properties of Silymarin With a Natural Phytochemical Ratio Over Commercial Formulations. [PDF]
J Cosmet DermatolABSTRACT Background Silymarin, a bioactive mixture widely used in anti‐aging cosmetic products, is primarily composed of silybin, silychristin, and silydianin. The relative proportions of these three compounds in milk thistle seeds, the natural source of silymarin, differ significantly from those found in commercially available silymarin formulations ...
Hou S, Wang A, Song H, Li A.
europepmc +2 more sources
An Innovative Serum With Retinol, Hydroxypinacolone Retinoate, Peptides, and Silybin Improves Mild Photoaged Facial Skin in Middle-Aged Chinese Women. [PDF]
J Cosmet DermatolABSTRACT Background Retinoids are effective anti‐aging agents, but their use is often limited by irritation, particularly in Asian skin. Hydroxypinacolone retinoate (HPR), a novel retinoid ester, offers similar benefits with reduced irritation, yet its combined use with retinol remains poorly characterized. Additionally, the integration of peptides and
Shen Y +9 more
europepmc +2 more sources
Foods, 2023 Milk thistle is a traditional medicinal herb. Silybin is a medicinal component found in the seed coat of milk thistle, which has liver-protective and anti-cancer properties.
Yanxia Liu +12 more
doaj +1 more source
Antioxidants, 2023 Oxidative stress is the major incentive for intestinal dysfunction in weaned piglets, which usually leads to growth retardation or even death. Silybin has caught extensive attention due to its antioxidant properties. Herein, we investigated the effect of
Long Cai +8 more
doaj +1 more source
Molecules, 2020 Silybin is a flavonolignan extracted from Silybum marianum with chemopreventive activity against various cancers, including breast. This study was designed to develop an HPLC-MS/MS method for the determination of silybin in human plasma, urine and breast
Matteo Lazzeroni +11 more
doaj +1 more source
Agronomy, 2021 Silybin A and B are two major hepatoprotective flavonolignans produced predominantly in Silybum marianum fruits. Similar to other plant secondary metabolites, silybin production is enhanced by biotic or abiotic stresses under the expanse of plant growth ...
Yun-Kiam Yap +3 more
doaj +1 more source
Oxidative stress: new insights on the association of nonalcoholic fatty liver disease and atherosclerosis [PDF]
, 2015 Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH), which may progress ...
Albanese, Fabiana +7 more
core +1 more source
Medical Sciences Forum, 2023 The health-promoting properties of Silybum marianum have been acknowledged since antiquity. This plant is credited with substantial hepatoprotective properties and is also protective in cardiovascular diseases, diabetes mellitus, and neurodegeneration ...
Agnieszka Mlicka +4 more
doaj +1 more source