Results 21 to 30 of about 14,059 (132)

Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication.

PLoS Pathogens, 2016
Within the first three weeks of human immunodeficiency virus (HIV) infection, virus replication peaks in peripheral blood. Despite the critical, causal role of virus replication in determining transmissibility and kinetics of progression to acquired ...
Adam J Ericsen, Michael Lauck, Mariel S Mohns, Sarah R DiNapoli, James P Mutschler, Justin M Greene, Jason T Weinfurter, Gabrielle Lehrer-Brey, Trent M Prall, Samantha M Gieger, Connor R Buechler, Kristin A Crosno, Eric J Peterson, Matthew R Reynolds, Roger W Wiseman, Benjamin J Burwitz, Jacob D Estes, Jonah B Sacha, Thomas C Friedrich, Jason M Brenchley, David H O'Connor   +20 more
doaj   +1 more source

Dot immunobinding assay compared with enzyme-linked immunosorbent assay for rapid and specific detection of retrovirus antibody induced by human or simian acquired immunodeficiency syndrome [PDF]

Journal of Clinical Microbiology, 1988
A rapid, specific, and sensitive modification of the dot immunobinding assay was compared with the standard enzyme immunoassay as a screening procedure for the detection of antibody in human or simian acquired immunodeficiency syndrome. Comparative testing with the available enzyme immunoassay procedures, either in commercial kit form or as provided by
R L, Heberling, S S, Kalter, P A, Marx, J K, Lowry, A R, Rodriguez   +4 more
openaire   +2 more sources

Small Ruminant Lentiviruses (SRLVs) Break the Species Barrier to Acquire New Host Range

Viruses, 2013
Zoonotic events of simian immunodeficiency virus (SIV) from non-human primates to humans have generated the acquired immunodeficiency syndrome (AIDS), one of the most devastating infectious disease of the last century with more than 30 million people ...
Juliano Cezar Minardi da Cruz, Dinesh Kumar Singh, Ali Lamara, Yahia Chebloune   +3 more
doaj   +1 more source

Morphological Changes of an Inflammatory Myopathy in Rhesus Monkeys with Simian Acquired Immunodeficiency Syndrome

Experimental Biology and Medicine, 1987
Eleven of 25 rhesus monkeys which died of simian acquired immunodeficiency syndrome (SAIDS) caused by infection with a type D retrovirus related to Mason-Pfizer monkey virus showed evidence of muscle weakness and atrophy and had elevated levels of muscle enzymes.
M C, Dalakas, M, Gravell, W T, London, G, Cunningham, J L, Sever   +4 more
openaire   +2 more sources

Growth regulation of simian and human AIDS-related non-Hodgkin's lymphoma cell lines by TGF-β1 and IL-6

BMC Cancer, 2007
Background AIDS-related non-Hodgkin's lymphoma (AIDS-NHL) is the second most frequent cancer associated with AIDS, and is a frequent cause of death in HIV-infected individuals. Experimental analysis of AIDS-NHL has been facilitated by the availability of
Levy Laura S, Puetter Adriane, Ruff Kristin R   +2 more
doaj   +1 more source

Coupling of Single Molecule, Long Read Sequencing with IMGT/HighV-QUEST Analysis Expedites Identification of SIV gp140-Specific Antibodies from scFv Phage Display Libraries

Frontiers in Immunology, 2018
The simian immunodeficiency virus (SIV)/macaque model of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome pathogenesis is critical for furthering our understanding of the role of antibody responses in the prevention of HIV infection,
Seung Yub Han, Alesia Antoine, David Howard, Bryant Chang, Woo Sung Chang, Matthew Slein, Gintaras Deikus, Sofia Kossida, Patrice Duroux, Marie-Paule Lefranc, Robert P. Sebra, Melissa L. Smith, Ismael Ben F. Fofana   +12 more
doaj   +1 more source

Transmission of Simian Acquired Immunodeficiency Syndrome (Saids) with Type D Retrovirus Isolated from Saliva or Urine

Experimental Biology and Medicine, 1984
Saliva and urine specimens from rhesus monkeys with SAIDS were found to contain a type D retrovirus related to Mason-Pfizer monkey virus (MPMV) which has been linked etiologically to SAIDS. Virus isolates from saliva and urine were shown to have the characteristics of the SAIDS agent by their reverse transcriptase divalent cation preference for ...
M, Gravell, W T, London, G, Lecatsas, R S, Hamilton, S A, Houff, J L, Sever   +5 more
openaire   +2 more sources

Low level expression of the Mitochondrial Antiviral Signaling protein (MAVS) associated with long-term nonprogression in SIV-infected rhesus macaques

Virology Journal, 2018
Background Abnormally increased immune activation is one of the main pathological features of acquired immunodeficiency syndrome (AIDS). This study aimed to determine whether long-term nonprogression (LTNP) suppresses the upregulation of immune ...
Miaomiao Zhang, Zhuotao Fu, Jiantao Chen, Boqiang Zhu, Ye Cheng, Linchun Fu   +5 more
doaj   +1 more source

Traditional Chinese Medicine etiology and pathogenesis of acquired immune deficiency syndrome in simian immunodeficiency virus-infected Chinese rhesus macaques

Journal of Traditional Chinese Medicine, 2012
To investigate the traditional Chinese Medicine (TCM) etiology and pathogenesis of acquired immune deficiency syndrome (AIDS) by 18-month observation of Chinese rhesus macaques infected with simian immunodeficiency virus (SIV) mac239.Thirty-five healthy Chinese rhesus macaques were divided into a model group (n = 30) and a control group (n = 5).
Li, Maoqing, Fu, Linchun, Hu, Yinjie, Zhang, Miaomiao, He, Jinyang, Chen, Zhixi, Chen, Jinyan   +6 more
openaire   +2 more sources

Multimorbidity and animal models

Animal Models and Experimental Medicine, Volume 8, Issue 12, Page 2196-2208, December 2025.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source