Results 1 to 10 of about 8,133 (173)

RETRACTED: High-throughput sequencing in diagnostics and prevention of herpes simplex virus infection (Herpesviridae, Alphaherpesvirinae, Simplexvirus, Human alphaherpesvirus 1)

Вопросы вирусологии, 2020
RETRACTED Herpes simplex viruses types 1 (HSV-1) and 2 (HSV-2) are among the most common viruses in the human population. The clinical manifestations of HSV infection vary widely, which necessitates reliable molecular methods for the timely diagnosis of ...
O. V. Sergeyev, R. E. Bosh’ian, I. F. Barinsky   +2 more
doaj   +6 more sources

Antiviral effect of novel purine conjugate LAS-131 against Herpes simplex virus type 1 (Herpesviridae: Alphaherpesvirinae: Simplexvirus: Human alphaherpesvirus 1) in vitro

Вопросы вирусологии, 2021
Introduction. Herpes simplex viruses type 1 (HSV-1) are extremely widespread throughout the world and, similar to other herpesviruses, establish lifelong persistent infection in the host.
V. L. Andronova, G. A. Galegov, V. V. Musiyak, O. A. Vozdvizhenskaya, G. L. Levit, V. P. Krasnov   +5 more
doaj   +7 more sources

Antiviral activity of the organic germanium complex with aciclovir against herpes simplex virus (Herpesviridae: Alphaherpesvirinae: Simplexvirus: Human alphaherpesvirus 1/2) in the in vitro and in vivo systems

Вопросы вирусологии, 2021
Introduction. A significant increase in the incidence of various forms of herpesvirus infection (HVI) determines the need to search for new approaches to the modification of one of the basic antiviral drugs aciclovir (ACV) and its dosage forms to improve
L. M. Alimbarova, I. V. Ambrosov, S. K. Matelo, I. F. Barinsky   +3 more
doaj   +7 more sources

Antiviral activity of extracts of basidiomycetes and humic compounds substances against Human Immunodeficiency Virus (Retroviridae: Orthoretrovirinae: Lentivirus: Human immunodeficiency virus 1) and Herpes Simplex Virus (Herpesviridae: Simplexvirus: Human alphaherpesvirus 1)

Вопросы вирусологии, 2020
Introduction. One of the most urgent problem of modern medicine is the fight against the disease caused by the Human Immunodeficiency Virus (HIV) – HIV infection. The chemical compounds have improved the situation for infected people, but they are toxic,
D. N. Nosik, N. N. Nosik, T. V. Teplyakova, O. A. Lobach, I. A. Kiseleva, N. G. Kondrashina, M. S. Bochkova, G. G. Ananko   +7 more
doaj   +6 more sources

Seroprevalence of herpes simplex virus type 1 (Herpesviridae: Simplexvirus: Human alphaherpesvirus 1) in smokers

Вопросы вирусологии
Introduction. Herpes simplex virus type 1 (HSV-1) is one of the most common human viral infections and has a double-stranded DNA genome belonging to the Herpesviridae family.
Jalil B. Mays, Mohammed Ali N. Mariem, Hadi I. Alabadi   +2 more
doaj   +5 more sources

Intrinsically disordered regions are abundant in simplexvirus proteomes and display signatures of positive selection [PDF]

Virus Evolution, 2020
Abstract Whereas the majority of herpesviruses co-speciated with their mammalian hosts, human herpes simplex virus 2 (HSV-2, genus Simplexvirus) most likely originated from the cross-species transmission of chimpanzee herpesvirus 1 to an ancestor of modern humans. We exploited the peculiar evolutionary history of HSV-2 to investigate the
Mozzi A, Forni D, Cagliani R, Clerici M, Pozzoli U, Sironi M   +5 more
semanticscholar   +6 more sources

CRISPR/Cas-9 vector system: targets UL-39 and inhibits Simplexvirus humanalpha1 (HSV-1) replication in vitro

Cellular and Molecular Biology, 2023
Simplexvirus humanalpha1 (HSV-1) affects approximately 67% of the world's population. Here, we sought to use the CRISPR / Cas9 system with the UL39 target, essential for virus replication.
Jéssica, Vasques Raposo, Luciana, Rodrigues Carvalho Barros, Lauana, Ribas Torres, Rafaela, Barbosa da Silva Pinto, Amanda, De Oliveira Lopes, Elen, Mello de Souza, Martin, Hernan Bonamino, Vanessa, Salete de Paula   +7 more
semanticscholar   +5 more sources

Pathogenesis, Diseases, Immune Response, and Chemotherapy of Genus Simplexvirus

Acta Microbiologica Bulgarica, 2023
Throughout evolution, members of the genus Simplexvirus have evolved a highly effective pathoge¬netic strategy based on biomolecular interactions with pathogen-sensitive biological species. This in turn leads to pathogen-associated recurrent diseases with a wide range of clinical manifestations, including her¬petic encephalitis (HSE), herpetic ...
N. Hristova, A.S. Galabov
semanticscholar   +3 more sources

Genus Simplexvirus: Life cycle

Acta Microbiologica Bulgarica, 2023
The two same-name members of the subfamily Alphaherpesvirinae, the human herpesviruses Herpes simplex virus-1 (HSV-1) and Herpes simplex virus-2 (HSV-2), use human epithelial cells to establish their lytic phase, and neuronal cells to establish a lysogenic (latent) phase.
N. Hristova, A.S. Galabov
semanticscholar   +3 more sources

Antiviral Efficacy of Coridothymus capitatus Essential Oil Against HSV-1 and HSV-2 [PDF]

Life
Coridothymus capitatus is a perennial herb with aromatic leaves and flowers, distinct from Thymus vulgaris in its chemical composition, resulting in a unique Thymus Essential Oil (TEO).
Virginia Fuochi, Pio Maria Furneri, Salvatore Furnari, Adriana Garozzo   +3 more
doaj   +3 more sources