HSV-NIS, an oncolytic herpes simplex virus type 1 encoding human sodium iodide symporter for preclinical prostate cancer radiovirotherapy [PDF]
Several clinical trials have shown that oncolytic herpes simplex virus type 1 (oHSV-1) can be safely administered to patients. However, virus replication in tumor tissue has generally not been monitored in these oHSV clinical trials, and the data suggest
Decklever, T D +4 more
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Herpes Simplex Virus Type 1 and Other Pathogens are Key Causative Factors in Sporadic Alzheimer’s Disease [PDF]
This review focuses on research in epidemiology, neuropathology, molecular biology, and genetics regarding the hypothesis that pathogens interact with susceptibility genes and are causative in sporadic Alzheimer’s disease (AD).
Harris, Elizabeth A., Harris, Steven A.
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Population-level effect of HSV-2 therapy on the incidence of HIV in sub-Saharan Africa. [PDF]
BACKGROUND: Herpes simplex virus type 2 (HSV-2) infection increases acquisition and transmission of HIV, but the results of trials measuring the impact of HSV-2 therapy on HIV genital shedding and HIV acquisition are mixed, and the potential impact of ...
Bakker, R +8 more
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Emerging roles of pathogens in Alzheimer disease [PDF]
Chronic spirochetal infection can cause slowly progressive dementia, cortical atrophy and amyloid deposition in the atrophic form of general paresis.
Miklossy, Judith
core
Expression of ICP0 from the simian simplexvirus SA8 and a study of its transactivation activity
Human Herpes Simplex viruses and Simian Herpes Simplex viruses share a high degree of genome homology, but despite this, important differences arise when the viruses are compared at the level of gene expression and virulence in non-host primates. In Human Herpes viruses (HSV-1 and HSV-2); 5 genes (RL02, US01, RS01, UL54 and US12) are expressed with an ...
openaire +1 more source
David gegen Goliath : wie Viren das Immunsystem überlisten [PDF]
Infektionen mit Herpesviren sind bereits seit der Antike bekannt. So beschrieb zum Beispiel schon Hippokrates in seinem »Corpus Hippocraticum« die sich auf der Haut ausbreitenden Herpes Simplex Läsionen und gab der Krankheit ihren bis heute gültigen ...
Schölz, Christian, Tampé, Robert
core
Hormonal regulation of innate immune responses and toll-like receptors in the human endometrium [PDF]
Vita.The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public ...
Lange, Margaret J., 1981-
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Een patient met opportunistische infecties als gevolg van het verworven immuundeficientie syndroom [PDF]
Contains fulltext : 4432.pdf (publisher's version ) (Open ...
Franken, C. +3 more
core +1 more source

