Results 11 to 20 of about 7,543 (128)
Journal of Medical Virology, Volume 95, Issue 1, January 2023., 2023 Abstract The aim of this study was to evaluate the role of viral polymerase chain reaction (PCR) testing in patients with aseptic meningitis and identify opportunities for improvement in clinical management. All cerebrospinal fluid samples collected in 1 year from four teaching hospitals in Sydney, Australia, were reviewed.
Myong Gyu Kim +11 more
wiley +1 more source
Pathogenesis, Diseases, Immune Response, and Chemotherapy of Genus Simplexvirus
Acta Microbiologica Bulgarica, 2023 Throughout evolution, members of the genus Simplexvirus have evolved a highly effective pathoge¬netic strategy based on biomolecular interactions with pathogen-sensitive biological species. This in turn leads to pathogen-associated recurrent diseases with a wide range of clinical manifestations, including her¬petic encephalitis (HSE), herpetic ...
N. Hristova, A.S. Galabov
openaire +1 more source
Problems of Virology, 2021 Introduction. A significant increase in the incidence of various forms of herpesvirus infection (HVI) determines the need to search for new approaches to the modification of one of the basic antiviral drugs aciclovir (ACV) and its dosage forms to improve their biopharmaceutical characteristics and increase the effectiveness of therapy.
L. M. Alimbarova +3 more
openaire +4 more sources
Effect of genital herpes on cervicovaginal HIV shedding in women co-infected with HIV AND HSV-2 in Tanzania. [PDF]
, 2013 To compare the presence and quantity of cervicovaginal HIV among HIV seropositive women with clinical herpes, subclinical HSV-2 infection and without HSV-2 infection respectively; to evaluate the association between cervicovaginal HIV and HSV shedding ...
David Mabey +11 more
core +8 more sources
HSV-2 Infection of Human Genital Epithelial Cells Upregulates TLR9 Expression Through the SP1/JNK Signaling Pathway [PDF]
, 2020 It is known that herpes simplex virus type 2 (HSV-2) triggers the activation of Toll-like receptor (TLR) 9 signaling pathway and the consequent production of antiviral cytokines in dendritic cells.
Barreto, M +11 more
core +1 more source
Problems of Virology, 2020 RETRACTEDHerpes simplex viruses types 1 (HSV-1) and 2 (HSV-2) are among the most common viruses in the human population. The clinical manifestations of HSV infection vary widely, which necessitates reliable molecular methods for the timely diagnosis of herpes virus infection, as well as for detection of mutations in the genes responsible for drug ...
O. V. Sergeyev +2 more
openaire +5 more sources
"Virus hunting" using radial distance weighted discrimination [PDF]
, 2015 Motivated by the challenge of using DNA-seq data to identify viruses in human blood samples, we propose a novel classification algorithm called "Radial Distance Weighted Discrimination" (or Radial DWD).
Dittmer, D. P. +2 more
core +3 more sources
Immune- and nonimmune-compartment-specific interferon responses are critical determinants of herpes simplex virus-induced generalized infections and acute liver failure [PDF]
, 2016 The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis.
Leib, David A +3 more
core +3 more sources
An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]
, 2011 Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Arthur, J. +6 more
core +1 more source
Lipschutz ulcers: uncommon diagnosis of vulvar ulcerations [PDF]
, 2016 Aetiological diagnosis of genital ulcers is still a challenge in clinical practice. The cause is mostly infectious, but it may otherwise be a presentation of a wide variety of pathologies, such as autoimmune (eg, Behçet’s disease), cancer or ...
Costa, Sara +3 more
core +1 more source