Results 11 to 20 of about 8,133 (173)
Вопросы вирусологииHerpes simplex virus type 1 (HSV-1), newly named as Simplexvirus humanalpha1 is one of the most common pathogens in the human population, which can cause severe disease, often with fatal outcomes.
Natalia A. Demidova +3 more
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CRISPR/Cas9 Reduces Viral Load in a BALB/c Mouse Model of Ocular Herpes Infection [PDF]
BiomedicinesBackground/Objectives: Simplexvirus humanalpha1 (HSV-1) can cause herpetic keratitis, which is the most common cause of infectious blindness in developed countries.
Luiza Silveira Garcia +6 more
doaj +3 more sources
Generation, characterization, and application of caprine herpesvirus 1 secreted glycoprotein D [PDF]
Microbiology SpectrumCaprine herpesvirus 1 (CpHV-1), a member of the Herpesvirales order, Herpesviridae family, Alphaherpesvirinae subfamily, and Simplexvirus genus, is classically associated with two distinct clinical syndromes.
Sergio Minesso +6 more
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Phylogeographic analysis reveals an ancient East African origin of human herpes simplex virus 2 dispersal out-of-Africa [PDF]
Nature Communications, 2022 AbstractHuman herpes simplex virus 2 (HSV-2) is a ubiquitous, slowly evolving DNA virus. HSV-2 has two primary lineages, one found in West and Central Africa and the other found worldwide. Competing hypotheses have been proposed to explain how HSV-2 migrated out-of-Africa (i)HSV-2 followed human migration out-of-Africa 50-100 thousand years ago, or (ii)
Havens, Jennifer +5 more
openaire +7 more sources
Biotechnology & Biotechnological Equipment, 2023 Astragalus glycyphyllos L. is widely used in Bulgarian folk medicine. Extracts from this plant have antiproliferative, antitumor and immune stimulating effects in vitro and in vivo. The aim of this study was to examine the potential antiviral activity of
Aleksandar Shkondrov +8 more
doaj +2 more sources
Characteristics of the pulmonary microbiota in patients with mild and severe pulmonary infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 BackgroundLung infection is a global health problem associated with high morbidity and mortality and increasing rates of hospitalization. The correlation between pulmonary microecology and infection severity remains unclear.
Danting Zhan +6 more
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A novel herpesvirus in blue penguins putatively associated with myocardial degeneration and necrosis. [PDF]
J Vet Diagn InvestWe identified a novel herpesvirus in 2 deceased captive blue penguins (Eudyptula minor). Moderate-to-severe myocardiocyte atrophy and necrosis, and eosinophilic intranuclear inclusion bodies (INIBs), were seen in myocardiocytes in one bird ...
Seimon TA +6 more
europepmc +2 more sources
Structural basis of nectin-1 recognition by pseudorabies virus glycoprotein D. [PDF]
PLoS Pathogens, 2017 An early and yet indispensable step in the alphaherpesvirus infection is the engagement of host receptors by the viral envelope glycoprotein D (gD). Of the thus-far identified gD receptors, nectin-1 is likely the most effective in terms of its wide usage
An Li +8 more
doaj +2 more sources
Equine histones are mobilized within equid alphaherpesvirus 1 (EHV1) replication compartments [PDF]
Journal of VirologyEquid alphaherpesvirus 1 (EHV1) is a DNA virus that causes severe disease in equids. Some strains are neurotropic and cause disease in the central nervous system, whereas others are non-neurotropic and can cause negative reproductive outcomes. Mechanisms
Kristen L. Conn
doaj +2 more sources