Results 21 to 30 of about 8,133 (173)

Impact of Toll-Like Receptors (TLRs) and TLR Signaling Proteins in Trigeminal Ganglia Impairing Herpes Simplex Virus 1 (HSV-1) Progression to Encephalitis: Insights from Mouse Models

Frontiers in Bioscience-Landmark
Herpes simplex virus 1 (HSV-1) or simplexvirus humanalpha 1 is a neurotropic virus that is responsible for orofacial infections in humans. More than 70% of the world’s population may have seropositivity for HSV-1, and this virus is a leading cause of ...
Marco Antônio Campos, Guilherme de Pádua Zolini, Erna Geessien Kroon   +2 more
doaj   +2 more sources

Jämförelse av kommersiella och InHouse kontroller för realtids-PCR vid diagnostik av Herpes simplexvirus 1 och 2

, 2018
Herpes simplexvirus 1 och 2 orsakar godartade sjukdomar, men kan även orsaka mortalitet. Diagnostik av herpes simplexvirus 1 och 2 utförs numera framför allt med realtids- Polymerase chain reaction (PCR). I metoden amplifieras specifika deoxiribonukleinsyra(DNA)-sekvenser till miljontals kopior vilka sedan detekteras med fluorescein.
Karlsson, Samuel, Palma Jansson, Nelly
openaire   +2 more sources

A broad wastewater screening and clinical data surveillance for virus-related diseases in the metropolitan Detroit area in Michigan [PDF]

Human Genomics
Background Periodic bioinformatics-based screening of wastewater for assessing the diversity of potential human viral pathogens circulating in a given community may help to identify novel or potentially emerging infectious diseases.
Yabing Li, Brijen Miyani, Russell A. Faust, Randy E. David, Irene Xagoraraki   +4 more
doaj   +2 more sources

Development of rhesus macaque astrocyte cell lines supporting infection with a panel of viruses. [PDF]

PLoS ONE
Non-human primate (NHP)-based model systems are highly relevant for biomedical research. However, only few NHP cell lines are available and the generation of additional cell lines is an urgent need to help in the refinement and replacement of these ...
Stefanie Reiter, Ting Sun, Sabine Gärtner, Stefan Pöhlmann, Michael Winkler   +4 more
doaj   +2 more sources

Bioinformatics-based screening tool identifies a wide variety of human and zoonotic viruses in Trujillo-Peru wastewater [PDF]

One Health
Peru was one of the most affected countries during the COVID-19 pandemic. Moreover, multiple other viral diseases (enteric, respiratory, bloodborne, and vector-borne) are endemic and rising.
Brijen Miyani, Yabing Li, Heidy Peidro Guzman, Ruben Kenny Briceno, Sabrina Vieyra, Rene Hinojosa, Irene Xagoraraki   +6 more
doaj   +2 more sources

Seroprevalence of herpes simplex virus type 1 (Herpesviridae: Simplexvirus: Human alphaherpesvirus 1) in smokers.

Voprosy virusologii
Herpes simplex virus type 1 (HSV-1) is one of the most common human viral infections and has a double-stranded DNA genome belonging to the Herpesviridae family. Smoking is one of the leading causes of disease and premature death worldwide, responsible for the death of up to six million people annually.
Jalil B. Mays, Mohammed Ali N. Mariem, Hadi I. Alabadi   +2 more
openaire   +3 more sources

Exploring the Antiviral Potential of Tungsten Oxide Nanoparticles Against Herpes Simplex Virus Type 1: A Promising Alternative to Acyclovir. [PDF]

IET Nanobiotechnol
Herpes simplex virus type 1 (HSV‐1) is responsible for the majority of cold sores, herpetic keratitis‐induced blindness, profound skin lesions, and encephalitis that can be fatal. Currently, acyclovir and its derivatives are the first‐line therapy for the treatment of HSV‐1 infection.
Jwaziri AK, Khales P, Kiani SJ, Yaghouti H, Babaei R, Salavatiha Z, Tavakoli A.   +6 more
europepmc   +2 more sources

A review of latency in the Alloherpesviridae family. [PDF]

J Fish Dis
Abstract The ability to impact the immune response of the host has been recognized as essential for the success of a virus during infection. A few groups of viruses can combine these immunomodulatory mechanisms with specific patterns of their own transcriptional and replication regulation to achieve persistence within the host long term.
Quijano Cardé EM, Soto E.
europepmc   +2 more sources

Association between human genetic variants affecting the host NK cell response and the development of herpes simplex virus type 1 encephalitis

Journal of Medical Virology, Volume 95, Issue 5, May 2023., 2023
Abstract Herpes simplex virus encephalitis (HSE) is a rare complication of herpes simplex virus type 1 (HSV‐1) infection or reactivation. It is so far unclear why only few patients develop HSE. As natural killer (NK) cells provide an important defense against HSV‐1, we investigated whether there is an association between distinct human genetic variants
Marianne Graninger, Hannes Vietzen, Elisabeth Puchhammer‐Stöckl   +2 more
wiley   +1 more source

De Novo synthesis of VP16 coordinates the exit from HSV latency in vivo [PDF]

, 2009
The mechanism controlling the exit from herpes simplex virus latency (HSV) is of central importance to recurrent disease and transmission of infection, yet interactions between host and viral functions that govern this process remain unclear. The cascade
Preston, C.M., Sawtell, N.M., Thompson, R.L.   +2 more
core   +6 more sources