Results 1 to 10 of about 46,710 (255)
Expert Opinion on Drug Safety, 2009 Treatments with ezetimibe/simvastatin (combined or alone) have been indicated as very promising approaches to strongly reduce cholesterol levels in hyperlipidemic patients.We will discuss the efficacy and safety of ezetimibe/simvastatin and their potential to reduce atheroprogression.
MONTECUCCO, FABRIZIO +2 more
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Annals of Internal Medicine, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Katarina, LeBlanc, Mary T, Brophy
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AbstractFor Abstract see ChemInform Abstract in Full Text.
Katarina, LeBlanc, Mary T, Brophy
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Expert Opinion on Pharmacotherapy, 2004
Simvastatin is a long-established hydroxy-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, first introduced in 1988. At the maximal recommended dose of 80 mg/day, it produces an average reduction in low-density lipoprotein cholesterol (LDL-C) of 47%, accompanied by reductions in very LDL-C, triglycerides and apolipoprotein B, and a modest ...
Terje R, Pedersen, Jonathan A, Tobert
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Simvastatin is a long-established hydroxy-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, first introduced in 1988. At the maximal recommended dose of 80 mg/day, it produces an average reduction in low-density lipoprotein cholesterol (LDL-C) of 47%, accompanied by reductions in very LDL-C, triglycerides and apolipoprotein B, and a modest ...
Terje R, Pedersen, Jonathan A, Tobert
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Simvastatin-tacrolimus and simvastatin-cyclosporin interactions in rats
Biopharmaceutics & Drug Disposition, 1998The effect of simvastatin (SV)-tacrolimus (TL) and simvastatin-cyclosporin (CyA) interactions on creatine phosphokinase levels and renal and hepatic function were investigated in rats. Animals were divided into seven groups; (1) SV (150 mg kg-1 oral) alone, (2) SV + TL (150 mg kg-1 oral + 0.5 mg kg-1 intraperitoneal (i.p.)), (3) TL (0.5 mg kg-1 i.p ...
H, Yamada, H, Kotaki, Y, Sawada, T, Iga
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The potential use of simvastatin for cancer treatment: A review
Biomedicine and Pharmacotherapy, 2021Jaqueline Aparecida Duarte +2 more
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