Rapid Field Immunoassay for Detecting Antibody to Sin Nombre Virus in Deer Mice [PDF]
We developed a 1-hour field enzyme immunoassay (EIA) for detecting antibody to Sin Nombre virus in deer mice (Peromyscus maniculatus). The assay specificity and sensitivity were comparable to those of a standard EIA.
Tony Schountz +6 more
doaj +4 more sources
Population Dynamics of the Deer Mouse (Peromyscus maniculatus) and Sin Nombre Virus, California Channel Islands [PDF]
Hantavirus pulmonary syndrome, first documented in 1993, is caused by Sin Nombre virus (SNV), which is carried by the Peromyscus species. In 1994, high SNV antibody prevalence was identified in deer mice from two California Channel Islands.
Tim B. Graham, Bruno B. Chomel
doaj +4 more sources
Vesicular Stomatitis Virus-Based Vaccines Provide Cross-Protection against Andes and Sin Nombre Viruses [PDF]
Andes virus (ANDV) and Sin Nombre virus (SNV) are the main causative agents responsible for hantavirus cardiopulmonary syndrome (HCPS) in the Americas.
Bryce M Warner +9 more
doaj +5 more sources
Experimental parasite community perturbation reveals associations between Sin Nombre virus and gastrointestinal nematodes in a rodent reservoir host. [PDF]
Individuals are often co-infected with several parasite species, yet measuring within-host interactions remains difficult in the wild. Consequently, such interactions’ impacts on host fitness and epidemiology are often unknown. We used anthelmintic drugs
Sweeny AR +5 more
europepmc +2 more sources
Structural and functional characterization of the Sin Nombre virus L protein. [PDF]
The Bunyavirales order is a large and diverse group of segmented negative-strand RNA viruses. Several virus families within this order contain important human pathogens, including Sin Nombre virus (SNV) of the Hantaviridae. Despite the high epidemic potential of bunyaviruses, specific medical countermeasures such as vaccines or antivirals are missing ...
Meier K +10 more
europepmc +7 more sources
A lethal disease model for hantavirus pulmonary syndrome in immunosuppressed Syrian hamsters infected with Sin Nombre virus. [PDF]
Brocato RL +5 more
europepmc +4 more sources
Sin Nombre Virus Pathogenesis inPeromyscus maniculatus [PDF]
ABSTRACT Sin Nombre virus (SNV), a member of the Hantavirus genus, causes acute viral pneumonia in humans and is thought to persistently infect mice. The deer mouse, Peromyscus maniculatus , has been identified as the primary reservoir host for SNV. To understand SNV infection of
Dale Netski +2 more
semanticscholar +3 more sources
Evaluating Neutralizing Antibodies in Hantavirus-Infected Patients Using Authentic Virus and Recombinant Vesicular Stomatitis Virus Systems [PDF]
Hantaviruses, including the Sin Nombre virus (SNV) and Andes virus (ANDV), are associated with severe global health risks, causing high mortality rates in hantavirus pulmonary syndrome (HPS) patients.
Punya Shrivastava-Ranjan +10 more
doaj +2 more sources
Autophagic Clearance of Sin Nombre Hantavirus Glycoprotein Gn Promotes Virus Replication in Cells [PDF]
ABSTRACT Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins, Gn and Gc. Cells transfected with plasmids expressing either GPC or both Gn and Gc revealed that Gn is posttranslationally degraded. Treatment of cells with the autophagy inhibitors 3-methyladenine, LY-294002, or Wortmanin rescued Gn ...
Islam T. M. Hussein +6 more
openalex +3 more sources
Numerous studies have linked biodiversity with zoonotic disease control. However, researchers have warned against simply believing that the increase in biodiversity can reduce the infection disease in the community.
L. Lee, M. H. Mohd
semanticscholar +3 more sources

