Sin Nombre Virus Pathogenesis in Peromyscus maniculatus [PDF]
ABSTRACT Sin Nombre virus (SNV), a member of the Hantavirus genus, causes acute viral pneumonia in humans and is thought to persistently infect mice. The deer mouse, Peromyscus maniculatus , has been identified as the primary reservoir host for SNV. To understand SNV infection of
D, Netski, B H, Thran, S C, St Jeor
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Seroprevalence against Sin Nombre virus in resident and dispersing deer mice. [PDF]
Through dispersal, deer mice (Peromyscus maniculatus) enter peridomestic settings (e.g., outbuildings, barns, cabins) and expose humans and other deer mouse populations to Sin Nombre virus (SNV). In June 2004, research on deer mouse dispersal was initiated at 2 locations in Montana.
Lonner BN +3 more
europepmc +4 more sources
Complete sequence of the genome of the human isolate of Andes virus CHI-7913: comparative sequence and protein structure analysis [PDF]
Indexación: ScieloWe report here the complete genomic sequence of the Chilean human isolate of Andes virus CHI-7913. The S, M, and L genome segment sequences of this isolate are 1,802, 3,641 and 6,466 bases in length, with an overall GC content of 38.7%.
Fernández, Jorge +9 more
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Hantavirus pulmonary syndrome: Current situation among rodent reservoirs and human population in the Xth Region, Chile [PDF]
In Chile, three Hantavirus seropositive rodent species (O longicaudatus, A olivaceus and A longipilis) are distributed from the Pacific coast to the Andes mountains and represent nearly 90% of the rodents captured in the Xth Region.
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Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]
Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Amy B. Pedersen +12 more
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Sin nombre virus glycoprotein trafficking
Sin Nombre virus (SNV) is a major representative of the New World hantaviruses and the most common cause of hantavirus pulmonary syndrome (HPS) with high mortality in North America. Unlike other members of the family Bunyaviridae which mature in the Golgi complex, New World hantaviruses have been previously reported to mature at the cell surface.
Spiropoulou, C.F +4 more
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Sin Nombre Virus mRNA Synthesis
Sin Nombre (SN) virus is the major etiologic agent of hantavirus pulmonary syndrome, a severe respiratory disease with high mortality. Like other hantaviruses, SN virus causes an inapparent chronic infection of the natural rodent reservoir and tends to grow slowly and produce little cytopathic effect even in highly susceptible Vero E6 tissue culture ...
Hutchinson, Karen L. +2 more
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Temporal analysis of Andes virus and Sin Nombre virus infections of Syrian hamsters. [PDF]
ABSTRACTAndes virus (ANDV) and Sin Nombre virus (SNV) are rodent-borne hantaviruses that cause a highly lethal hemorrhagic fever in humans known as hantavirus pulmonary syndrome (HPS). There are no vaccines or specific drugs to prevent or treat HPS, and the pathogenesis is not understood.
Wahl-Jensen V +6 more
europepmc +4 more sources
Complete genetic characterization and analysis of isolation of Sin Nombre virus [PDF]
This study reports completion of the genetic characterization of the entire genome of Sin Nombre (SN) virus (NMH10) detected in autopsy tissues from a patient who died of hantavirus pulmonary syndrome (HPS). The large (L) genome segment was found to be 6,562 nucleotides in length and encoded a putative L polymerase that was 2,153 amino acids in length.
V E, Chizhikov +5 more
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Biodefense Implications of New-World Hantaviruses
Hantaviruses, part of the Bunyaviridae family, are a genus of negative-sense, single-stranded RNA viruses that cause two major diseases: New-World Hantavirus Cardiopulmonary Syndrome and Old-World Hemorrhagic Fever with Renal Syndrome.
Michael Hilary D’Souza +3 more
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