Results 51 to 60 of about 22,347 (256)

Antiviral activity of glycopeptide antibiotics derivates against Sindbis virus

International Journal of Infectious Diseases
Introduction: Thousands of human infective viruses spread worldwide, yet protective measures exist for only a fraction, with internationally accepted vaccines available for an even smaller subset.
Ms Krisztina Leiner, Mr Valentin Molnár, Mr Zoltán Kopasz, Mrs Ilona Bakai-Bereczki, Ms Eszter Lőrincz, Dr. Eszter Szabó, Dr. Mónika Madai, Dr. Anikó Borbás, Dr. Anett Kuczmog   +8 more
doaj   +1 more source

Changes in Cellular mRNA Stability, Splicing, and Polyadenylation through HuR Protein Sequestration by a Cytoplasmic RNA Virus

Cell Reports, 2013
The impact of RNA viruses on the posttranscriptional regulation of cellular gene expression is unclear. Sindbis virus causes a dramatic relocalization of the cellular HuR protein from the nucleus to the cytoplasm in infected cells.
Michael D. Barnhart, Stephanie L. Moon, Alexander W. Emch, Carol J. Wilusz, Jeffrey Wilusz   +4 more
doaj   +1 more source

Immunogenicity of a DNA-Based Sindbis Replicon Expressing Crimean–Congo Hemorrhagic Fever Virus Nucleoprotein

Vaccines, 2021
Crimean–Congo hemorrhagic fever virus (CCHFV) infrequently causes hemorrhagic fever in humans with a case fatality rate of 30%. Currently, there is neither an internationally approved antiviral drug nor a vaccine against the virus.
Thomas Tipih, Mark Heise, Felicity Jane Burt   +2 more
doaj   +1 more source

Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges [PDF]

, 2014
Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal health, yet effective control measures have proven difficult to implement, and novel means of controlling their replication in arthropod vectors, such as mosquitoes, are
Dietrich, Isabelle, Kohl, Alain, Rainey, Stephanie M., Shah, Pranav   +3 more
core   +1 more source

Research on basis of reverse genetics system of a Sindbis-like virus XJ-160

Virology Journal, 2011
As a Sindbis-like virus (SINLV), XJ-160 virus was isolated from a pooled sample of Anopheles mosquitoes collected in Xinjiang, China, in 1990. Recombinant plasmid pBR-XJ160 is an infectious full-length cDNA clone of XJ-160 virus, from which rescued virus
Wu-yang Zhu, Guo-dong Liang
doaj   +1 more source

Agglutination of Sindbis Virus and of Cells Infected with Sindbis Virus by Plant Lectins [PDF]

Journal of Virology, 1973
We have examined the agglutination of Sindbis virus and of chick and hamster cells infected with Sindbis virus by two of the plant lectins, concanavalin A and Ricinus communis agglutinin. Both lectins agglutinate the virus by binding to the polysaccharide chains of the envelope glycoproteins.
Birdwell, Charles R., Strauss, James H.
openaire   +2 more sources

Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]

, 1987
International audienceThe Dark Energy Camera has captured a large set of images as part of Science Verification (SV) for the Dark Energy Survey (DES). The SV footprint covers a large portion of the outer Large Magellanic Cloud (LMC), providing photometry
Abbott, T. M. C., Allam, S. S., Annis, J., Balbinot, Eduardo, Benoit-Levy, A., Bernstein, J. P., Bernstein, R. A., Bertin, E., Brooks, D., Buckley-Geer, E., Cunha, C. E., Da Costa, L. N., DePoy, D. L., Desai, S., Diehl, H. T., Doel, P., Drlica-Wagner, A., Estrada, J., Evrard, A. E., Finley, D. A., Flaugher, B., Frieman, J. A., Girardi, L., Gruen, D., Gruendl, R. A., Honscheid, K., James, D., Kuehn, K., Kuropatkin, N., Lahav, O., Maia, M. A. G., March, M., Marshall, J. L., Miller, C., Miquel, R., Neto, A. Fausti, Ogando, R., Peoples, J., Pieres, A., Plazas, A., Rosell, A. Carnero, Santiago, B. X., Scarpine, V., Schubnell, M., Sevilla-Noarbe, I., Smith, R. C., Soares-Santos, M., Suchyta, E., Swanson, M. E. C., Tarle, G., Tucker, D. L., Walker, A. R., Wechsler, R., Yanny, B., Zuntz, J.   +54 more
core   +4 more sources

Sindbis and Middelburg Old World Alphaviruses Associated with Neurologic Disease in Horses, South Africa

Emerging Infectious Diseases, 2015
Old World alphaviruses were identified in 52 of 623 horses with febrile or neurologic disease in South Africa. Five of 8 Sindbis virus infections were mild; 2 of 3 fatal cases involved co-infections.
Stephanie van Niekerk, Stacey Human, June Williams, Erna van Wilpe, Marthi Pretorius, Robert Swanepoel, Marietjie Venter   +6 more
doaj   +1 more source

Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosis. [PDF]

, 1998
Recent studies have established cell type- specific, proapoptotic, or antiapoptotic functions for the transcription factor NF-kappaB. In each of these studies, inhibitors of NF-kappaB activity have been present before the apoptotic stimulus, and so the ...
DiDonato, JA, Hardwick, JM, Hoffmann, A, Lin, KI, Ratan, RR   +4 more
core  

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source