Results 61 to 70 of about 22,215 (261)

The selectivity and specificity of autophagy in drosophila [PDF]

, 2012
Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou, Clark, Contamine, Deng, Dezelee, Finley, Fouillet, Goto, Kadandale, McPhee, Midorikawa, Nezis, Nisoli, Novak, Orvedahl, Pankiv, Park, Rello-Varona, Schweers, Shoji, Simonsen, Tian, Webb, Wild, Wyers, Yu, Yu, Ziviani   +27 more
core   +2 more sources

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

Advanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu, Guigen Zhang, Yuan Lin, Shiming Yi, Jingyu Yang, Xueying Lin, Deli Song, Zhiheng Liu, Jiayu Zhang, Ying Zeng, Shanyu Huang, Zhen Fan, Jifu Zhang, Ying Liu, Cheng Hu, Wenbo Zhu, Wei Yin, Jun Hu, Guangmei Yan, Jing Cai, Jiankai Liang   +20 more
wiley   +1 more source

Efficiency of Transduction by Recombinant Sindbis Replicon Virus Varies Among Cell Lines, Including Mosquito Cells and Rat Sensory Neurons

BioTechniques, 1996
Recombinant alphaviruses have been used as vehicles for delivery and expression of heterologous genes in mammalian, avian and insect cell lines. We have used a Sindbis replicon virus (Sinreplac) able to express the E.
J. Corsini, D.L. Traul, C.L. Wilcox, P. Gaines, J.O. Carlson   +4 more
doaj   +1 more source

Zoonotic Disease Transmission May Be Linked to Host Co‐Occurrence Network Topology

Annals of the New York Academy of Sciences, Volume 1554, Issue 1, Page 110-120, December 2025.
A global analysis of zoonotic host co‐occurrence networks identified 22 networks from five continents (A) and 87 hosts from 16 orders of mostly birds but also mammals (B) as having a high potential for disease transmission. ABSTRACT Most human pathogens are zoonotic, transmitted from vertebrate hosts to humans.
Patrick T. Stillson, Brent B. Crow, William R. Budnick, Sophia I. Passy   +3 more
wiley   +1 more source

Cell-specific targeting of lentiviral vectors mediated by fusion proteins derived from Sindbis virus, vesicular stomatitis virus, or avian sarcoma/leukosis virus

Retrovirology, 2010
Background The ability to efficiently and selectively target gene delivery vectors to specific cell types in vitro and in vivo remains one of the formidable challenges in gene therapy.
Marino Michael P, Bialkowska Agnieszka, Kutner Robert H, Zhang Xian-Yang, Klimstra William B, Reiser Jakob   +5 more
doaj   +1 more source

Mutagenesis of the conserved 51-nucleotide region of Sindbis virus [PDF]

, 1990
We have constructed 25 site-specific mutations in a domain of 51 nucleotides in Sindbis virus that is highly conserved among all alphaviruses sequenced to date.
Niesters, Hubert G. M., Strauss, James H.   +1 more
core  

An All‐in‐One Metabarcoding Approach to Mosquito and Arbovirus Xenosurveillance

Molecular Ecology Resources, Volume 25, Issue 8, November 2025.
ABSTRACT Next‐generation sequencing (NGS) has the potential to transform mosquito‐borne disease surveillance but remains under‐utilised. This study introduces a comprehensive multi‐loci metabarcoding‐based MX (molecular xenomonitoring) approach to mosquito and arbovirus surveillance, enabling parallel identification of mosquito vectors, circulating ...
Brian J. Johnson, Melissa C. Graham, Elina Panahi, Carla Julia S. P. Vieira, Nisa Suraj Nath, Paul Mason, Jamie Gleadhill, Darran Thomas, Michael B. Onn, Martin A. Shivas, Damien Shearman, Jonathan M. Darbro, Gregor J. Devine   +12 more
wiley   +1 more source

Defined mutations in the 5' nontranslated sequence of Sindbis virus RNA [PDF]

, 1990
We have constructed 24 deletion mutants which contain deletions of from 1 to 15 nucleotides in the 5' nontranslated region of Sindbis virus RNA and tested the effect of these mutations on virus replication.
Niesters, Hubert G. M., Strauss, James H.   +1 more
core   +2 more sources

A Viral mRNA Motif at the 3′-Untranslated Region that Confers Translatability in a Cell-Specific Manner. Implications for Virus Evolution [PDF]

, 2016
Sindbis virus (SINV) mRNAs contain several motifs that participate in the regulation of their translation. We have discovered a motif at the 3′ untranslated region (UTR) of viral mRNAs, constituted by three repeated sequences, which is involved in the ...
Carrasco, Luis, Garcia-Moreno, Manuel, Sanz, Miguel Angel   +2 more
core   +2 more sources

Sindbis Virus nsP2 Endopeptidase

, 2013
The third edition of the Handbook of Proteolytic Enzymes aims to be a comprehensive reference work for the enzymes that cleave proteins and peptides, and contains over 800 chapters. Each chapter is organized into sections describing the name and history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing
Strauss, Ellen G., Strauss, James H.
openaire   +2 more sources