Results 81 to 90 of about 22,215 (261)

Histopathological Alterations and Dysregulation of Type I Interferon Signaling in the Human Cerebral Cortex During Severe Dengue

Journal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT Dengue virus (DENV) is a major arthropod‐borne pathogen, endemic in over 100 countries and posing global health challenges. While innate immune responses and viral evasion mechanisms have been extensively studied in animal models and mononuclear cells, severe dengue can affect multiple tissues, including the central nervous system (CNS ...
Leandro Mantovani de Castro, Elaine Raniero Fernandes, Juarez Antonio Simoes Quaresma, Carmen Lucia Penteado Lancelotti, Maria Irma Seixas Duarte, Leda Viegas de Carvalho, Ricardo Penny, Pedro Fernando da Costa Vasconcelos, Evandro Sobroza de Mello, Mirian Nacagami Sotto, Carla Pagliari   +10 more
wiley   +1 more source

Mosquitoborne Viruses, Czech Republic, 2002

Emerging Infectious Diseases, 2005
Specimens from residents (n = 497) of an area affected by the 2002 flood were examined serologically for mosquitoborne viruses. Antibodies were detected against Tahyna (16%), Sindbis (1%), and Batai (0.2%) viruses, but not West Nile virus. An examination
Zdenek Hubálek, Petr Zeman, Jiří Halouzka, Zina Juřicová, Eva Šťovíčková, Helena Bálková, Silvie Šikutová, Ivo Rudolf   +7 more
doaj   +1 more source

Sindbis virus proteins nsP1 and nsP2 contain homology to nonstructural proteins from several RNA plant viruses [PDF]

, 1985
Although the genetic organization of tobacco mosaic virus (TMV) differs considerably from that of the tripartite viruses (alfalfa mosaic virus [AlMV] and brome mosaic virus [BMV]), all of these RNA plant viruses share three domains of homology among ...
Ahlquist, Paul, Haseloff, James, Rice, Charles M., Strauss, Ellen G., Strauss, James H., Zimmern, David   +5 more
core   +1 more source

Phospholipid Synthesis in Sindbis Virus-Infected Cells [PDF]

Journal of Virology, 1970
We investigated the metabolic requirements for the decrease in phospholipid synthesis previously observed by Pfefferkorn and Hunter in primary cultures of chick embryo fibroblasts infected with Sindbis virus. The incorporation of 32 PO 4 into all classes of phospholipids was found to decline ...
M R, Waite, E R, Pfefferkorn
openaire   +2 more sources

Mapping the Habitat Suitability of Culex pipiens in Europe Using Ensemble Bioclimatic Modelling

Journal of Biogeography, Volume 52, Issue 10, October 2025.
ABSTRACT Aim Anthropogenic pressure on natural ecosystems has profoundly influenced the dynamics of disease vectors, altering their distribution, phenology, and increasing the risk of vector‐borne diseases. This study aims to investigate the climatic and environmental determinants of Culex pipiens distribution in continental Europe, to inform and ...
Lara Marcolin, Agnese Zardini, Eleonora Longo, Beniamino Caputo, Piero Poletti, Moreno Di Marco   +5 more
wiley   +1 more source

Mutations in the E2 glycoprotein and the 3\u27 untranslated region enhance chikungunya virus virulence in mice [PDF]

, 2017
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection.
Carpentier, Kathryn S, Diamond, Michael S, Fox, Julie M, Hawman, David W, May, Nicholas A, Montgomery, Stephanie A, Moorman, Nathaniel J, Morrison, Thomas E, Sanders, Wes   +8 more
core   +3 more sources

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes. [PDF]

, 2015
BackgroundDendritic simplification, a key feature of the neurodegenerative triad of Alzheimer's disease (AD) in addition to spine changes and neuron loss, occurs in a region-specific manner.
Bakota, Lidia, Ballatore, Carlo, Brandt, Roland, Golovyashkina, Nataliya, Penazzi, Lorène, Smith, Amos B   +5 more
core   +1 more source

Extracellular Vesicles in Arthropods: Biogenesis, Functions, Isolation Methods and Applications

Journal of Extracellular Vesicles, Volume 14, Issue 9, September 2025.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound nanoparticles secreted by cells that are involved in multiple forms of intercellular communication and show promising potential for biotechnological applications. Arthropod‐derived EV research remains relatively fragmented in contrast to the extensively studied mammalian EV field. In this review,
Simon Remans, Stijn Van den Brande, Jozef Vanden Broeck, Dulce Santos   +3 more
wiley   +1 more source

Microassay for Sindbis virus and interferon activity [PDF]

Journal of Clinical Microbiology, 1983
A simple and rapid microplaque assay for Sindbis virus was developed which uses microtiter plates and overlay medium consisting of methylcellulose and specific antibody to Sindbis virus. Discrete plaque formation was consistently observed on baby hamster kidney (BHK-15) cells within 24 h. The assay was reproducible, quantitative, and had about the same
R E, Lloyd, D A, Weigent, G J, Stanton
openaire   +2 more sources