Journal of Insect Science, 2001 Sindbis virus expression vectors have been used successfully to express and silence genes of interest in vivo in several mosquito species, including Aedes aegypti, Ae. albopictus, Ae. triseriatus, Culex pipiens, Armigeres subalbatus and Anopheles gambiae.
L.L. Cheng +7 more
doaj
Site-directed mutagenesis of the proposed catalytic amino acids of the Sindbis virus capsid protein autoprotease [PDF]
, 1990 The structural proteins of Sindbis virus are translated as a polyprotein precursor that is cleaved upon translation. The capsid protein is postulated to be a serine protease that releases itself from the N terminus of the nascent polyprotein by ...
Hahn, Chang S., Strauss, James H.
core
Membrane-Mediated Alterations of Intracellular Na+ and K+ in Lytic-Virus-Infected and Retrovirus-Transformed Cells [PDF]
Infection of chick-embryo fibroblasts and other ceils by certain animal viruses results in alterations in the intracellular concentrations of Na + and K +.
Bose, Henry R. +2 more
core +1 more source
Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes. [PDF]
, 2015 BackgroundDendritic simplification, a key feature of the neurodegenerative triad of Alzheimer's disease (AD) in addition to spine changes and neuron loss, occurs in a region-specific manner.
Bakota, Lidia +5 more
core +1 more source
Extracellular Vesicles in Arthropods: Biogenesis, Functions, Isolation Methods and Applications
Journal of Extracellular Vesicles, Volume 14, Issue 9, September 2025.ABSTRACT Extracellular vesicles (EVs) are membrane‐bound nanoparticles secreted by cells that are involved in multiple forms of intercellular communication and show promising potential for biotechnological applications. Arthropod‐derived EV research remains relatively fragmented in contrast to the extensively studied mammalian EV field. In this review,
Simon Remans +3 more
wiley +1 more source
Viruses, 2019 Sindbis virus (SINV) is a mosquito-borne alphavirus circulating globally. SINV outbreaks have been mainly reported in North-European countries. In Israel, SINV was detected in 6.3% of mosquito pools; however, SINV infection in humans has rarely been ...
Ravit Koren +6 more
doaj +1 more source
Electron microscopic study of sindbis virus morphogenesis [PDF]
Archiv f�r die gesamte Virusforschung, 1973 An electron microscopic study of the growth and development of Sindbis virus in chick embryo fibroblast cultures demonstrated that the morphogenesis of this virus is essentially like that of other group A arboviruses hitherto studied.
M. Rubio-Huertos +2 more
openaire +3 more sources
Why enveloped viruses need cores -- the contribution of a nucleocapsid core to viral budding
, 2017 During the alphavirus lifecycle, a nucleocapsid core buds through the cell membrane to acquire an outer envelope of lipid membrane and viral glycoproteins. However, the presence of a nucleocapsid core is not required for assembly of infectious particles.
Hagan, Michael F. +2 more
core +1 more source
Targeting lentiviral vectors to antigen-specific immunoglobulins [PDF]
, 2008 Gene transfer into B cells by lentivectors can provide an alternative approach to managing B lymphocyte malignancies and autoreactive B cell-mediated autoimmune diseases.
Black M.E. +17 more
core +2 more sources
Zebrafish as a Versatile Model Organism: From Tanks to Treatment
MedComm – Future Medicine, Volume 4, Issue 3, September 2025.The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava +9 more
wiley +1 more source