Results 101 to 110 of about 1,166,241 (315)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Single-cell RNA sequencing methods discussed in this review.

Single-cell RNA sequencing methods discussed in this review.
Alistair B. Russell (11820364), Sharmada Swaminath (9856862)   +1 more
core   +1 more source

Integrative Analysis of Single-Cell and Bulk RNA Sequencing Reveals Prognostic Characteristics of Macrophage Polarization-Related Genes in Lung Adenocarcinoma

, 2023
Ke Mi, Lizhong Zeng, Yang Chen, Shuanying Yang Department of Respiratory and Critical Care Medicine, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of ChinaCorrespondence: Shuanying Yang, Department of ...
Mi K, Zeng L, Chen Y, Yang S
core  

Single-cell RNA sequencing of metastatic testicular seminoma reveals the cellular and molecular characteristics of metastatic cell lineage

, 2022
The Single-cell RNA sequencing data of metastatic testicular seminoma, including tumor tissues, pelvic lymph node (LN1) and renal hilus lymph ...
Zhenyuan Yu (6698111)
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Single-Cell RNA Sequencing Integrated with Bulk-RNA Sequencing Analysis Reveals Prognostic Signatures Based on PANoptosis in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma
Jiyin Wang,1– 5,* Xue Yin,1– 4,6,* Ziyi Li,1– 4,* Pu Liang,1– 4,* Yipeng Wang,1– 4 Xingling Li,1– 4 Wenying Qiao,1– 4 Chaoyang Xiong,1– 4 Minghang Yu,1– 4 Xiaoyan Ding,1– 4 Xi Wang1– 4,7 1National Key Laboratory of ...
Wang J, Yin X, Li Z, Liang P, Wang Y, Li X, Qiao W, Xiong C, Yu M, Ding X, Wang X   +10 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Single‐Cell Sequencing in Normal and Malignant Hematopoiesis

HemaSphere, 2018
AbstractHematopoiesis is one of the best studied adult stem‐cell systems, with a differentiation hierarchy progressing from immature hematopoietic stem cells to over 10 distinct mature cell types. Recent technological breakthroughs now make it possible to define transcriptional profiles in thousands of individual cells.
Wilson, Nicola K, Göttgens, Berthold
openaire   +3 more sources

Sequencing Single Cells Reveals Sequential Stem Cell States

, 2015
Understanding the molecular mechanisms underlying activation of quiescent neural stem cells (NSCs) is complicated by heterogeneity in coexisting NSC pools.
Linnarsson, Sten, Linnarsson, S,
core   +1 more source

A guiding role of the Arabidopsis circadian clock in cell differentiation revealed by time-series single-cell RNA sequencing

, 2022
Circadian rhythms and progression of cell differentiation are closely coupled in multicellular organisms. However, whether establishment of circadian rhythms regulates cell differentiation or vice versa has not been elucidated due to technical ...
26838, 26837, 26839, 80551499, 26830, Kondo, Yuki, Fukuda, Hiroo, 26832, Haraguchi, Kazuya, 26831, 26834, 26833, Bekki, Keita, 26836, 26835, Araki, Takashi, Endo, Motomu, Inoue, Keisuke, Shimizu, Hanako, Saito, Masato, Uemoto, Kyohei, 26841, Kubota, Akane, 26840, 26842, Torii, Kotaro, 2, Suzuki, Takamasa, Kubo, Minoru   +28 more
core   +1 more source