Results 261 to 270 of about 1,166,241 (315)

Identification and validation of key PANoptosis-related genes via integrative machine learning and single-cell sequencing in AILI. [PDF]

iScience
Li S, He C, Wang M, Ran B, Li G, Dong G, Zhang H, Mei C, Song Y, Yu Q, Chen S, Zhu C, Li J.   +12 more
europepmc   +1 more source

Oxidative stress-associated genes TPPP3 and VEGFA in COPD revealed by bulk and single-cell sequencing analysis. [PDF]

Sci Rep
Choi W, Wu Y, Chen W, Shi Y, Luo W, Wu X, Ruan Z, Dong J.   +7 more
europepmc   +1 more source

Editorial: Single-cell sequencing of the immune microenvironment in cancer. [PDF]

Front Immunol
Coffey DG.
europepmc   +1 more source

Single-Cell Sequencing Redefines Immune Heterogeneity and Communication Networks in ARDS: Toward Precision Therapeutics. [PDF]

Int J Genomics
Chen HB, Xu AM, Qiu HB, Chao J, Zhao S.
europepmc   +1 more source

Exploring the Dynamic Changes of Intercellular Connections in Cervical Cancer: Insights From Transcriptomic Data Combined With Single-Cell Sequencing. [PDF]

Hum Mutat
Ji R, Geng R, Zhang Z, Gao F, Zhang P, Sun Y, Liu J, Zhang L.   +7 more
europepmc   +1 more source

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Single-Cell Sequencing for Everybody

2021
Over the past 7 years, single-cell sequencing has become very popular. For this reason, many laboratories of different biological disciplines that span from neurobiology to developmental biology from immunology to tumor biology have been approaching this technique. For someone new to this field that wants to investigate heterogeneity in what appears to
Valentina, Proserpio, Carlotta, Duval, Vanessa, Falvo, Giacomo, Donati, Salvatore, Oliviero   +4 more
openaire   +2 more sources

The promise of single-cell sequencing

Nature Methods, 2013
Individual cells of the same phenotype are commonly viewed as identical functional units of a tissue or organ. However, the deep sequencing of DNA and RNA from single cells suggests a more complex ecology of heterogeneous cell states that together produce emergent system-level function.
James, Eberwine, Jai-Yoon, Sul, Tamas, Bartfai, Junhyong, Kim   +3 more
openaire   +2 more sources

Advancement of Single-Cell Sequencing in Medulloblastoma

2022
Single-cell sequencing is a promising attempt to investigate the genomic, transcriptomic, and multiomic level of individual cell in the larger population of cells. The outward evolution of the technique from a manual method to the automation of single-cell sequencing is cogent.
Deepanshu, Verma, Namyashree, Nayak, Ashuthosh, Singh, Ashutosh Kumar, Singh, Neha, Garg   +4 more
openaire   +2 more sources

Sequencing the Genomes of Single Cells

2019
Single-cell genome sequencing can detect low-frequency genetic alterations present in complex tissues. However, the experimental procedures are technically challenging. This includes dissociation of the tissue, isolation of single cells, whole-genome amplification, sequencing library preparation, and an optional target enrichment.
Veronica, Gonzalez-Pena, Charles, Gawad
openaire   +2 more sources