Results 71 to 80 of about 6,253,377 (301)

Elucidation of the Mechanism of an Epigenetic Switch by Single-molecule Assays [PDF]

Biophysical Journal, 2009
The lambda bacteriophage epigenetic switch determines the growth lifestyle of the virus after infection of its host (E. coli). It is now clear that the switch consists of a ∼2.3 kbp-long DNA loop mediated by the lambda repressor protein. Using tethered particle microscopy (TPM), magnetic tweezers and AFM, our laboratory has novel, direct evidence of ...
Finzi, Laura, Zurla, Chiara, Manzo, Carlo, Dunlap, David   +3 more
openaire   +1 more source

The complexity of mesoporous silica nanomaterials unravelled by single molecule microscopy [PDF]

, 2011
Mesoporous silica nanomaterials are a novel class of materials that offer a highly complex porous network with nanometre-sized channels into which a wide amount of differently sized guests can be incorporated.
Bräuchle, Christoph, Timo Lebold, Jens Michaelis, Christoph Bräuchle, Michaelis, Jens, Lebold, Timo   +5 more
core   +1 more source

A Memristive Element Based on an Electrically Controlled Single‐Molecule Reaction [PDF]

, 2020
A single-molecule memory element is electrically-controlled using two distinct reaction mechanisms as reported by K. Moth-Poulsen, J. Hihath, and co-workers (DOI:10.1002/anie.202002300).
Haipeng B. Li, Joshua Hihath, Behabitu E. Tebikachew, Li, Haipeng B., Tebikachew, Behabitu Ergette, Kasper Moth‐Poulsen, Tebikachew, Behabitu Ergette,, Hihath, Joshua,, Hihath, Joshua, Wiberg, Cedrik, Cedrik Wiberg, Moth-Poulsen, Kasper,, Li, Haipeng B.,, Wiberg, Cedrik,, Moth-Poulsen, Kasper   +14 more
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

DNA Y Structure: A Multidimensional Single Molecule Assay [PDF]

Biophysical Journal, 2014
Single molecule techniques have enabled significant advancement in the understanding of biological systems. However, current optical trapping techniques allow for force, extension and torque to be measured only along the axis of applied tension. This one dimensional aspect limits studies of complex biological systems due to the difficulty of data ...
Inman, James, Smith, Ben, Hall, Michael, Forties, Robert A., Wang, Michelle D.   +4 more
openaire   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Protocol to generate fast-dissociating recombinant antibody fragments for multiplexed super-resolution microscopy

STAR Protocols, 2023
Summary: Multiplexed high-density label super-resolution microscopy image reconstruction by integrating exchangeable single-molecule localization (IRIS) enables elucidating fine structures and molecular distribution in cells and tissues.
Qianli Zhang, Akitoshi Miyamoto, Naoki Watanabe   +2 more
doaj   +1 more source

Versatile Control System for Automated Single-Molecule Optical Tweezers Investigations [PDF]

, 2010
We present a versatile control system to automate single-molecule biophysics experiments. This method combines low-level controls into various functional, user-configurable modules, which can be scripted in a domain-specific instruction language.
Steven J. Koch, Richard C. Yeh
core  

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source