Results 241 to 250 of about 5,402,175 (290)

Matrix‐Activated Aptamer Sensors for Human Serum Analysis

Angewandte Chemie, EarlyView.
The sample self‐analyzes: The predominant serum proteins, albumin and immunoglobulin G, were leveraged to activate the response of fluorescent aptamer probes within the biological matrix. The fluorescence‐anisotropy‐based sensing platform demonstrated both performance and consistency for the direct detection of small molecules in serum‐rich samples ...
Amandine Barbaroux, Benoit Chovelon, Emmanuelle Fiore, Sebastien Vezirian, Mickael Henry, Marwa Zoubeidi, Maria C. DeRosa, Corinne Ravelet, Eric Peyrin   +8 more
wiley   +1 more source

Prophage Activation Triggers Extracellular Synthesis of DNA in Bacterial Biofilms via Rolling Circle Replication

Angewandte Chemie, EarlyView.
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero, Line Mørkholt Lund, Lasse Hyldgaard Klausen, Obinna Markraphael Ajunwa, Mingdong Dong, Rikke Louise Meyer, Victoria Birkedal, Kai Thormann   +7 more
wiley   +1 more source

pH‐Driven Actuation of Unmodified DNA Origami Rectangles

Angewandte Chemie, EarlyView.
Unmodified DNA origami rectangles exhibit a reversible transition between planar and tubular states driven by near‐neutral pH changes. This behavior arises from crossover‐mediated mechanical coupling of overwound DNA and extends to dimers and nanoribbons, enabling the formation of nanotube architectures without added motifs or chemical modification ...
Diego A. Uehara, Yasmin H. Khazid, Willi R. Berg, Veronika Valova, Felix J. Rizzuto   +4 more
wiley   +1 more source

Supramolecular Mechanophore Additives Enable Mechanochromic Hydrogels

Angewandte Chemie, EarlyView.
A supramolecular loop‐forming mechanophore featuring a quencher and an emitter is incorporated as a water‐soluble macromolecular additive into hydrogels. In the stress‐free state, intramolecular charge‐transfer interactions fold the loop and quench fluorescence.
Iulia Scarlat, Jess M. Clough, Christoph Weder   +2 more
wiley   +1 more source

Correction to 'RNase E searches for cleavage sites in RNA by linear diffusion: direct evidence from single-molecule FRET'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

Force‐Induced Control of Circularly Polarized Luminescence With Rotaxane Architecture

Angewandte Chemie, EarlyView.
Force‐induced reversible on/off switching of circularly polarized luminescence is achieved with a rotaxane‐based supramolecular mechanophore. The mechanophore, featuring a chiral helicene luminophore, is incorporated as a first network cross‐linker into a double‐network organogel.
Keigo Nonaka, Takumi Kuroda, Kota Masuda, Toshiki Nishitani, Masaki Enokido, Makoto Tsurui, Yuichi Kitagawa, Yasuchika Hasegawa, Keiichi Noguchi, Koji Nakano, Yoshimitsu Sagara   +10 more
wiley   +1 more source

Enzyme activation by urea reveals the interplay between conformational dynamics and substrate binding: a single-molecule FRET study

Scheerer D, Levy D, Casier R, Riven I, Mazal H, Haran G.   +5 more
europepmc   +1 more source

Interplay between conformational dynamics and substrate binding regulates enzymatic activity: a single-molecule FRET study. [PDF]

Chem Sci
Scheerer D, Levy D, Casier R, Riven I, Mazal H, Haran G.   +5 more
europepmc   +1 more source

High-Resolution Single-Molecule FRET via DNA eXchange (FRET X)

Nano Letters, 2021
Single-molecule FRET is a versatile tool to study nucleic acids and proteins at the nanometer scale. However, currently, only a couple of FRET pairs can be reliably measured on a single object, which makes it difficult to apply single-molecule FRET for ...
Sung Hyun Kim, Mike Filius, Ivo Severins   +2 more
exaly   +3 more sources

Single‐Molecule Four‐Color FRET [PDF]

Angewandte Chemie - International Edition, 2010
We developed a single-molecule four-color FRET technique both in confocal and in total-internal-reflection fluorescence microscopies. Real-time determination of six inter-fluorophore FRET efficiencies allowed us to probe the correlated motion of four arms of the Holliday junction.
Sanghwa Lee, Sungchul Hohng, Jingyi Fei   +2 more
exaly   +3 more sources