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Exploring single-domain antibody thermostability by molecular dynamics simulation

Journal of Biomolecular Structure and Dynamics, 2019
Ammar Mohseni   +2 more
exaly  

Single domain antibodies for the treatment of Hemophilia A

Anticorps à domaine unique pour le traitement de l'hémophilie A L'hémophilie A est une maladie hémorragique rare liée au chromosome X, consécutive à l'absence de facteur VIII (FVIII) pro-coagulant. La prévention ou le traitement des hémorragies chez les patients atteints d'hémophilie A sont obtenus par l'injection de molécules ...
openaire   +1 more source

Differential tumor-targeting abilities of three single-domain antibody formats

Cancer Letters, 2010
Mehdi Arbabi-Ghahroudi   +2 more
exaly  

Single Domain Antibodies - Methods and Protocols

2012
The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined ...
openaire   +1 more source

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