Results 91 to 100 of about 214,395 (302)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Position dependent measurement of single event transient voltage pulse shapes under heavy ion irradiation

open access: yes, 2012
A CMOS inverter in 90 nm CMOS bulk technology was exposed to heavy ion radiation (Au-197) at a micro-beam facility. The targeted inverter occupies an area of 6×3 µm².
Zimmermann, Horst   +5 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Single Event Multiple Transient Analysis using Satisfiability Modulo Theories

open access: yes, 2019
Due to the radioactive nature of the space environment, the integrated circuits in space suffer from reliability problems. This threat is due to the presence of high energy ionizing particles like cosmic ray neutrons and their interaction with the ...
Nethula, Sowmith
core  

Single event transient reliability analysis on a fault-tolerant RISC-V microprocessor design

open access: yes
The miniaturization of electronic devices and the improved operating speeds increase the likelihood of single event faults. Differently from Single Event Upset (SEU) faults, Single Event Transient (SET) faults generally affect combinational logic, making
Mastrandrea, Antonio   +6 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Simultaneous ionospheric and magnetospheric observations of azimuthally propagating transient features during substorms [PDF]

open access: yes, 1998
International audienceDuring the 6th August 1995, the CUTLASS Finland HF radar ran in a high time resolution mode, allowing measurements of line-of-sight convection velocities along a single beam with a temporal resolution of 14 s.
Tim K. Yeoman (7583066)   +9 more
core   +1 more source

Single event transients monitoring and diagnostic in FPGA

open access: yesFacta universitatis - series: Electronics and Energetics, 2018
Analysis of single event transients (SETs) generated in field programmable gate arrays (FPGA) under heavy charged particles (HCP) irradiation and SET suppression methods is performed. The circuit for FPGA SET detection is designed for transients generated both inside FPGA and outside at package pin level.
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Técnicas de inyección de fallos basadas en FPGAs para la evaluación de la tolerancia a fallos de tipo SEU en circuitos digitales [PDF]

open access: yes, 2007
Este trabajo de tesis doctoral presenta nuevas técnicas de inyección de fallos transitorios en elementos de memoria, que permiten la evaluación del comportamiento de los complejos circuitos digitales actuales en presencia de fallos SEU (Single Event ...
Portela García, Marta
core  

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