381. Inhibiting HIV-1 Infection in Human T-Cells by Lentiviral-Mediated Delivery of siRNA Against CCR5 and Rev [PDF]
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DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding+5 more
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361. siRNA Silencing of Fas on Pancreatic Islet Cells for Improving Islet Transplantation in Diabetes [PDF]
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This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang+22 more
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Articles selected by Faculty of 1000: chemical modification analysis of siRNAs; allele-specific variation in gene expression; gut parasite comparative genomics; functional promoter variants; microRNA finction in leaf development [PDF]
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Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi+4 more
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823. Characterizing Pol II and Pol III Driven siRNA: Application to Spinal Cerebellar Ataxia Type I [PDF]
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The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong+8 more
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