Results 141 to 150 of about 34,817 (248)
siRNA Delivery and Targeting [PDF]
Molecular Pharmaceutics, 2009 Ram I. Mahato, Kun Cheng
openaire +3 more sources
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Advanced Materials, EarlyView.Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang +4 more
wiley +1 more source
Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery
Advanced Materials, EarlyView.This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae +6 more
wiley +1 more source
Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference [PDF]
, 2004 Kumiko Ui‐Tei +7 more
openalex +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens [PDF]
, 2004 Andrew C. Hsieh
openalex +1 more source