Results 141 to 150 of about 527,047 (339)

Additional file 19 of Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2

, 2022
Vijaya Sai Ayyagari
openalex   +1 more source

siRNA [PDF]

Chemistry & Biology, 2002
Ramaswamy, Gopalakrishna, Slack, Frank J
openaire   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

Advanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández, Mariarosaria De Simone, Yilian Fernández‐Afonso, Daniel Garcia‐Gonzalez, Pablo Martínez‐Vicente, Thomas van Zanten, Raluca M. Fratila, Maria Moros   +7 more
wiley   +1 more source

Lentiviral-mediated delivery of siRNAs for antiviral therapy [PDF]

, 2006
Kevin V. Morris, John J. Rossi
openalex   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Evidence Supporting the Safety of Pegylated Diethylaminoethyl-Chitosan Polymer as a Nanovector for Gene Therapy Applications

International Journal of Nanomedicine, 2020
Elsa Patricia Rondon,1 Houda Abir Benabdoun,1 Francis Vallières,1 Maicon Segalla Petrônio,2 Marcio José Tiera,2 Mohamed Benderdour,1 Julio Cesar Fernandes1 1Orthopedic Research Laboratory, Hôpital Du Sacré-Cœur De ...
Rondon EP, Benabdoun HA, Vallières F, Segalla Petrônio M, Tiera MJ, Benderdour M, Fernandes JC   +6 more
doaj  

Delivery of Quantum Dot-siRNA Nanoplexes in SK-N-SH Cells for BACE1 Gene Silencing and Intracellular Imaging [PDF]

, 2012
Shengliang Li, Zhonghua Liu, Fengtao Ji, Zijian Xiao, Minjuan Wang, Yingji Peng, Yulin Zhang, Ling Liu, Zibing Liang, Feng Li   +9 more
openalex   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Reduced FBXW7 expression in pancreatic cancer correlates with poor prognosis, and chemotherapeutic resistance via accumulation of MCL1 [PDF]

, 2018
学位記番号 ...
Ishii, Norihiro, イシイ, ノリヒロ, 石井, 範洋   +2 more
core  

An FGFR1-Binding Peptide Modified Liposome for siRNA Delivery in Lung Cancer [PDF]

, 2022
Zhipeng Dong, Yunxue Yin, Jun Luo, Bingxia Li, Fangning Lou, Qiyan Wang, Qingfa Zhou, Baofen Ye, Yue Wang   +8 more
openalex   +1 more source