Results 231 to 240 of about 497,452 (342)

NIR-Triggered siRNA Release and Lysosomal Escape for Synergistic Photothermal Tumor Therapy. [PDF]

Int J Nanomedicine
Baldan M, Zhang S, Sun Q, Su Y, Mei D, Sun R, Zheng A, Liu D, Zhang J, Huo R, Tian Y, Han L, Wang S, Wang Y, Cui C.   +14 more
europepmc   +1 more source

410. Multivalent siRNAs for Combinatorial HIV Gene Therapy [PDF]

, 2004
Joseph S. Anderson, Akhil C. Banerjea, Mingjie Li, John J. Rossi, Ramesh Akkina   +4 more
openalex   +1 more source

COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo, Wen‐Ying Zheng, Qiong Zhang, Yan Yuan, Mei‐Qi Li, Kai Du, An‐Ran Gao, Li‐Jun Pei, Jie Xie, Wen‐Hao Chen, Long Zhang, Xiu‐Zhu Guo, Xiao‐Ran Yang, Chao Zeng, Guo‐Hua Yang, Min Deng   +15 more
wiley   +1 more source

321. siFECT™: Optimised Formulation for the Delivery of siRNA at Minimum Doses and Maximum Specificity [PDF]

, 2004
Sebastien Spagnou, Michael R. Jorgensen, Andrew D. Miller, Michael Keller   +3 more
openalex   +1 more source

MTFR2‐Mediated Fission Drives Fatty Acid and Mitochondrial Co‐Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis

Advanced Science, EarlyView.
In the tumor margin of hepatocellular carcinoma (HCC), activated hepatic stellate cells upregulate MTFR2, initiating inhibiting DRP1 degradation and mitochondrial fission. This enhances mitochondrial availability and facilitates FAs synthesis via ACC1. Additionally, fission promotes RAC1‐mediated cytoskeletal remodeling and Miro1‐mediated mitochondrial
La Zhang, Baoyong Zhou, Jun Yang, Cong Ren, Jing Luo, Zhenghang Li, Qiang Liu, Zuotian Huang, Zhongjun Wu, Ning Jiang   +9 more
wiley   +1 more source

Differential RNAi efficacy of siRNA and dsRNA targeting key genes for pest control in <i>Spodoptera litura</i>. [PDF]

Front Insect Sci
Lin YC, Lu YH, Liu Y, Su YJ, Lin YH, Wu YL.   +5 more
europepmc   +1 more source

Anti-RhoA and Anti-RhoC siRNAs Inhibit the Proliferation and Invasiveness of MDA-MB-231 Breast Cancer Cells in Vitro and in Vivo

, 2004
J.-Y. Pillé, Christophe Denoyelle, Julia Varet, J.‐R. Bertrand, J. Soria, Paule Opolon, Lu H, Linda-Louise Pritchard, J. P. Vannier, Claude Malvy, Claudine Soria, H. Li   +11 more
openalex   +1 more source

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activity. [PDF]

Angiogenesis
Chambers SEJ, Guduric-Fuchs J, Pedrini E, Bertelli PM, Charoensuk C, Peixoto E, Pathak V, Alhamdan HI, Xie R, Krasnodembskaya A, Lechner J, Stitt AW, Medina RJ.   +12 more
europepmc   +1 more source

Articles selected by Faculty of 1000: profiling flowers; targeted transgenesis in Drosophila; aging and oxidation in plants; membrane protein localization in E. coli; immune response to siRNAs [PDF]

, 2004

openalex   +1 more source