Results 51 to 60 of about 28,818 (194)

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

Advanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen, Yiming Huang, Yang Zhang, Chunhao Yu, Hanqi Liu, Dong Bian, Di Wu, Wu Wang, Xunming Ji, Yufeng Zheng, Miaowen Jiang, Ming Li   +11 more
wiley   +1 more source

Liver transplantation [PDF]

, 2014
Purpose of review: Long-term survival of liver transplant recipients is threatened by increased rates of de-novo malignancy and recurrence of hepatocellular carcinoma (HCC), both events tightly related to immunosuppression.
Burroughs, AK, De la Mata, M, Rodríguez-Perálvarez, M   +2 more
core  

Pancreas and islet cell transplantation [PDF]

, 2002
Currently, for the patient with type 1 diabetes, a definitive treatment without resorting to the use of exogenous insulin can be achieved only with pancreas or islet cell transplantation.
A.N. Balamurugan, Alexander, Allen, Amos, Barber, Barrou, Bartlett, Björk, Bonner-Weir, Brekke, Calne, Calne, Cameron, Cheung, Chow, Corry, Diem, Diem, DiLandro, Fontes, Giannoukakis, Giannoukakis, Gibson, Gliedman, Grey, Groth, Groth, Gu, Gupta, Harris, Hayek, Henry, Ilieva, Kelly, Kemp, Kendall, Kendall, Keymeulen, Kirk, Koike, Koike, Lacy, Lafferty, Lakey, Lillehei, London, Massimo Trucco, Mazariegos, Mintz, Murray, Najarian, Nghiem, Paraskevas, Petruzzo, Piehlmeier, Pipeleers-Marichal, Posselt, Prevost, Rajotte, Ramiya, Ramos, Ricordi, Rita Bottino, Robertson, Shapiro, Simeonovic, Solders, Sollinger, Sollinger, Sollinger, Soria, Ssobolew, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Stone, Stratta, Stratta, Sutherland, Suzuki, Tchervenivanov, Terasaki, Thomas E. Starzl, Tyden, Tzakis, Yasunami   +94 more
core   +1 more source

Pure Red Cell Aplasia Associated With Thymic Tumors, a Nationwide Retrospective Study

American Journal of Hematology, EarlyView.
ABSTRACT Pure red cell aplasia (PRCA) is the most frequent autoimmune cytopenia associated with thymic tumors (TTs). In a nationwide retrospective study, we included 41 patients (22 women, median age 62 years). At PRCA diagnosis, the mean hemoglobin level was 6.6 ± 2.1 g/dL, and the reticulocyte count was 6 ± 5 × 109/L. PRCA was diagnosed before TT (8%,
Mylène Hemmer, Sylvain Moinard, Olivier Lambotte, Marion Malphettes, Louis Terriou, Bertrand Lioger, Guillaume Le Guenno, Jean‐François Viallard, Marc Michel, Hervé Lobbes   +9 more
wiley   +1 more source

Comparative acute toxicity of intravenous paclitaxel and sirolimus in rats

Current Research in Toxicology
Aim: In view of the exploration of sirolimus (rapamycin) as balloon coating for peripheral intravasal treatment and the reports on unfavorable tolerance of daily low-dose sirolimus, the aim of the study was to investigate potential toxicological effects ...
Jing Xie, Denise Schuett, Ulrich Speck, Tobias Haase   +3 more
doaj   +1 more source

Development and Physicochemical Characterization of Sirolimus Solid Dispersions Prepared by Solvent Evaporation Method [PDF]

Advanced Pharmaceutical Bulletin, 2014
Purpose: The aim of the present investigation was preparation and characterization of sirolimus solid dispersions by solvent evaporation technique to improve its dissolution properties.
Shahram Emami, Hadi Valizadeh, Ziba Islambulchilar, Parvin Zakeri-Milani   +3 more
doaj   +1 more source

Automated processing of whole blood samples for the determination of immunosuppressants by liquid chromatography tandem-mass spectrometry [PDF]

, 2006
Background: Liquid chromatography tandem-mass spectrometry (LC-MS/MS) is an efficient technology for routine determination of immunosuppressants in whole blood; however, time-consuming manual sample preparation remains a significant limitation of this ...
Spöhrer, Ute, Vogeser, Michael
core   +1 more source

Everolimus‐Coated Laser‐Cut Self‐Expandable Metallic Stent Suppresses Stent‐Induced Tissue Hyperplasia in a Rat Gastric Outlet

Advanced NanoBiomed Research, EarlyView.
Everolimus‐coated laser‐cut self‐expandable metallic stents suppress stent‐induced tissue hyperplasia in the gastric outlet by reducing inflammation, fibrosis, and smooth muscle proliferation. Herein, we demonstrate the mechanical stability, sustained drug release, and histological benefits in a rat gastric outlet model, suggesting potential for ...
Yubeen Park, Chae Eun Yun, Dong‐Sung Won, Song Hee Kim, Ji Won Kim, Seung Jin Eo, Seokin Kang, Hyun‐Do Jung, Do Hoon Kim, Jun‐Kyu Park, Jung‐Hoon Park   +10 more
wiley   +1 more source

Drug Interaction between Sirolimus and Ranolazine in a Kidney Transplant Patient

Case Reports in Transplantation, 2014
Purpose. The case of a kidney transplant recipient who experienced a probable drug interaction between sirolimus and ranolazine is reported. Summary.
Joanna C. Masters, Mita M. Shah, Ashley A. Feist   +2 more
doaj   +1 more source

A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery [PDF]

, 2016
Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer.
Jones, Robert L., Kennedy, Simon, McCormick, Christopher, Mullen, Alexander B., Wadsworth, Roger M.   +4 more
core   +2 more sources