Results 51 to 60 of about 82,161 (336)

Similar trends in serum VEGF-D levels and kidney angiomyolipoma responses with longer duration sirolimus treatment in adults with tuberous sclerosis. [PDF]

PLoS ONE, 2013
We have previously shown that serum VEGF-D is elevated at baseline, correlates with kidney angiomyolipoma size at baseline and 12 months, and decreases with sirolimus treatment in adults with tuberous sclerosis complex (TSC).
Izabela A Malinowska, Nancy Lee, Vidhya Kumar, Elizabeth A Thiele, David Neal Franz, Stephen Ashwal, Arthur Sagalowsky, Francis J Dimario, Drew Cutler, Darcy Krueger, Susana Camposano, Jan Paolini, Sandra L Dabora   +12 more
doaj   +1 more source

Effects of Sirolimus Treatment on Fetal Hemoglobin Production and Response to SARS-CoV-2 Vaccination: A Case Report Study

Hematology Reports, 2023
The β-thalassemias are a group of monogenic hereditary hematological disorders caused by deletions and/or mutations of the β-globin gene, leading to low or absent production of adult hemoglobin (HbA).
Maria Rita Gamberini, Cristina Zuccato, Matteo Zurlo, Lucia Carmela Cosenza, Alessia Finotti, Roberto Gambari   +5 more
doaj   +1 more source

Efficacy of systemic sirolimus in the treatment of generalized lymphatic anomaly and Gorham–Stout disease

Pediatric Blood & Cancer, 2019
Generalized lymphatic anomaly (GLA) and Gorham–Stout disease (GSD) are rare complicated lymphatic malformations that occur in multiple body sites and are associated with significant morbidity and mortality.
Kiersten W Ricci, A. Hammill, P. Mobberley-Schuman, S. Nelson, J. Blatt, J. Bender, C. McCuaig, Anna Synakiewicz, I. Frieden, D. Adams   +9 more
semanticscholar   +1 more source

Severe adverse events during sirolimus “off‐label” therapy for vascular anomalies

Pediatric Blood & Cancer, 2020
Clinical studies have shown low toxicity and a favorable safety profile for sirolimus in vascular anomalies. Here, we describe severe adverse events (SAEs) observed during “off‐label use” for vascular anomalies.
J. Rössler, E. Baselga, Victoria Dávila, V. Celis, A. Diociaiuti, M. El Hachem, S. Mestre, Dario Haeberli, A. Prokop, C. Hanke, Wolfgang Loichinger, I. Quéré, I. Baumgartner, C. Niemeyer, Friedrich G. Kapp   +14 more
semanticscholar   +1 more source

Posttransplant anemia: the role of sirolimus [PDF]

Kidney International, 2009
Posttransplant anemia is a common problem that may hinder patients' quality of life. It occurs in 12 to 76% of patients, and is most common in the immediate posttransplant period. A variety of factors have been identified that increase the risk of posttransplant anemia, of which the level of renal function is most important.
Arjang Djamali, Ajay K. Singh, Daniel W. Coyne, Jay B. Wish, Steven Fishbane, David J. Cohen   +5 more
openaire   +3 more sources

Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin®) [PDF]

, 2005
Modifications in the timing and dosage of immunosuppression can ameliorate the morbidity and mortality that has prevented widespread use of intestinal transplantation (ITx) in children.
Abu-Elmagd, K, Bond, GJ, Macedo, C, Mazariegos, GV, Murase, N, Peters, J, Reyes, J, Sindhi, R, Starzl, TE   +8 more
core   +1 more source

Activity of sirolimus in patients with progressive epithelioid hemangioendothelioma: A case‐series analysis within the Italian Rare Cancer Network

Cancer, 2020
The objective of this study was to report on a retrospective series of patients with epithelioid hemangioendothelioma (EHE) who received treatment with sirolimus within the Italian Rare Cancer Network.
S. Stacchiotti, N. Simeone, S. Lo Vullo, G. Baldi, A. Brunello, B. Vincenzi, E. Palassini, G. Dagrada, P. Collini, C. Morosi, F. Greco, M. Sbaraglia, A. D. Dei Tos, L. Mariani, A. Frezza, P. Casali   +15 more
semanticscholar   +1 more source

Avaliação da endotelização de hastes de stents em artérias ilíacas de coelhos Assessment of stent strut endothelialization in iliac arteries of rabbits

Arquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: A rápida endotelização pós-implante de stent é ocorrência desejável por teoricamente reduzir a possibilidade de trombose do stent. OBJETIVO: Avaliar a extensão da endotelização de hastes de stents eluidores de sirolimus (liberados da face ...
Celso Kiyochi Takimura, Ii-sei Watanabe, Francisco Rafael Martins Laurindo, Paulo Sampaio Gutierrez, Vera Demarchi Aiello, Spero Penha Morato, Pedro Alves Lemos Neto   +6 more
doaj   +3 more sources

Targeting phosphoinositide 3-kinase (PI3K) in head and neck squamous cell carcinoma (HNSCC). [PDF]

, 2018
The landscape of head and neck squamous cell carcinoma (HNSCC) has been changing rapidly due to growing proportion of HPV-related disease and development of new therapeutic agents.
Jung, Kyungsuk, Kang, Hyunseok, Mehra, Ranee   +2 more
core   +2 more sources

The use of sirolimus in patients with recurrent cytomegalovirus infection after kidney transplantation: A retrospective case series analysis

Saudi Journal of Kidney Diseases and Transplantation, 2019
Cytomegalovirus (CMV) is one of opportunistic infections post solid organ transplant and remains a cause of morbidity and mortality. Mammalian target of rapamycin inhibitors has a theoretical antiviral advantage compared to conventional immunosuppression.
Ali M Shendi, Rachel K. Y Hung, Ben Caplin, Paul Griffiths, Mark Harber   +4 more
doaj   +1 more source