Results 251 to 260 of about 72,220 (305)

NAA10 and BTRC drive CREBRF degradation in endoplasmic reticulum stress and renal tubular injury

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1268-1282, August 2026.
In diabetic kidney disease (DKD), the acetyltransferase NAA10 mediates the acetylation of CREBRF, promoting its recognition and binding by the E3 ubiquitin ligase BTRC, thereby enhancing the ubiquitination level of CREBRF and accelerating its degradation.
Sitian Fang, Jing Ning, Jinjing Huang, Yanxia Chen   +3 more
wiley   +1 more source

SIRT1-mediated deacetylation of HMGB1 promotes the progression of endometriosis by regulating autophagy. [PDF]

Sci Rep
Lan Y, Wang L, Huang Z, Ren S, Tang L.
europepmc   +1 more source

Molecular Mechanisms and Network Pharmacology Revealing Therapeutic Potential of Acetamidosulfonamides against Parkinsonian Model. [PDF]

ACS Omega
Ruankham W, Prachayasittikul V, Pingaew R, Tantimongcolwat T, Worachartcheewan A, Chompon K, Ruchirawat S, Prachayasittikul V, Prachayasittikul S, Phopin K.   +9 more
europepmc   +1 more source

miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis. [PDF]

Int J Mol Med
Wang X, Song L, Wang J, Xie Q, Wang Y, Li C, Wang T, Du Y.   +7 more
europepmc   +1 more source

Matched Analysis of Circulating and Adipose Tissue SIRT1 Protein Level in Human Obesity. [PDF]

Nutrients
Salvatori L, Megiorni F, Baldazzi GM, Ventimiglia V, Gangitano E, Watanabe M, Gandini O, Poggiogalle E, Gnessi L, Lubrano C, Gianfrilli D, Isidori AM, Angeloni A, Mariani S.   +13 more
europepmc   +1 more source

The role of NAD⁺ metabolic reprogramming in colorectal cancer chemoresistance: mechanistic insights, clinical translation challenges and opportunities. [PDF]

Front Oncol
Ma Z, Gong X, Liu F.
europepmc   +1 more source

Targeting SIRT1 stability: arctiin ameliorates doxorubicin-induced cardiac injury by inhibiting SMURF2 binding and enhancing protective lipid metabolism. [PDF]

Front Pharmacol
Teng T, Huo Y, Shen Z, Ni H, Yuan Y, Xu S, Zhang N, Tang Q.   +7 more
europepmc   +1 more source

Berberine and Metabolic Dysfunction‐Associated Steatotic Liver Disease: Hope or Hype?

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
Ruth Nona, Eric Kalo
wiley   +1 more source

Obesity- and Glucose-Dependent Differential Autophagy Marker Expression in Adipose Tissues and Adipocytes. [PDF]

Obes Sci Pract
Islami E, Schmid A, Steger D, Köhler S, Schäffler A, Karrasch T.   +5 more
europepmc   +1 more source