Results 161 to 170 of about 74,229 (355)
Effects of mitochondrial NADP+-dependent isocitrate dehydrogenase deficiency on fructose-induced obesity in mice [PDF]
, 2018 Obesity prevalence in the United States continues to increase and is associated with health consequences such as type 2 diabetes, hypertension, atherosclerosis, and hyperlipidemia.
Beane, Kaleigh Elizabeth +1 more
core +2 more sources
Epigenetic mechanisms of nephroprotection in diabetic nephropathy: focus is on sirtuin-1
, 2021 К. А. Айтбаев +4 more
openalex +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Sirtuin 5: a review of structure, known inhibitors and clues for developing new inhibitors [PDF]
, 2016 Lingling Yang +6 more
openalex +1 more source
Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue
iNew Medicine, EarlyView.ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao +3 more
wiley +1 more source
A Novel Inhibitor Of Sirtuin: Elucidation Of Mode Of Action And Molecular Pathway In Colorectal Cancer Cell Line [PDF]
, 2017 Kanser kolon merupakan salah satu jenis kanser yang paling banyak didapati di seluruh dunia Colorectal cancer (CRC) is one of the most common types of cancer ...
Tan, Yi Jer
core
Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity [PDF]
, 2022 Xiwen Xiong +21 more
openalex +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu +6 more
wiley +1 more source
LifeMetabolic dysfunction-associated steatotic liver disease (MASLD) is rapidly emerging as the most prevalent chronic liver disease, closely linked to the escalating rates of diabesity.
Zehuan Ding, Jian Zhang, Mahua Choudhury
doaj +1 more source