Results 181 to 190 of about 55,883 (307)

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

PGC-1α and PPARs cooperatively mediate photoreceptor neuroprotection in rd1 mouse inherited retinal degeneration. [PDF]

Cell Death Dis
Wang L, Yan J, Sancho-Pelluz J, Yang Q, Hu Z, Jiao K, Seeliger MW, Paquet-Durand F.   +7 more
europepmc   +1 more source

Evidence of a sirtuin gene family in grapevine (Vitis vinifera L.).

, 2009
Sirtuins are known as regulators of age-dependent gene transcription and chromatin modification in yeast and in animals, but information about their occurrence and role in plants is scarce.
Bavaresco, Luigi, Busconi, Matteo, Fogher, Corrado   +2 more
core  

Induced Pluripotent Stem Cells Derived CD71(\uff0b)CD235a(\uff0b) Erythroblasts Were Increased by Sirtuin 1 Activator

Induced pluripotent stem cells (iPSCs) are a promising cell source for regenerative medicine. Clinical applications require a large number of functional red blood cells (RBCs), making it essential to ensure the proliferation of actively dividing ...
Yoon, Young-sup, Park, Kyung Hwan, Kim, Changyeong, Han, A-Reum, Lee, Ji Yoon, Jeon, Soo-Been   +5 more
core   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Comparative Structure-Based Analysis of Predicted BZD9L1 Binding Modes Across Human Sirtuins. [PDF]

Int J Mol Sci
Tan YJ, Lee YT, Oon CE, Mancera RL.
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

The Sirtuin Network: Linking NAD⁺ Metabolism, Mitochondrial Function, and Metabolic Homoeostasis. [PDF]

Diabetes Metab Res Rev
Szczęsny-Małysiak E, Schiavoni V, Rotondo R, Zeppa SD, Vignini A, Moriconi E, Cecati M, Armani A, Gorini S, Campagna R, Caprio M.   +10 more
europepmc   +1 more source

Evaluation of serum levels of Sirtuin-1 in lung cancer patients

Background: Sirtuin-1 is a protein from the family of sirtuins that has been implicated in inflammaging and oxidative stress in cancer patients. The aim of this study was to investigate the serum level of Sirtuin-1 and its relation with quality of life ...
حسینی نیا, سعید, قبادی مراللو, حسن, اصلانی, محمدرضا, پورفرضی, فرهاد, عاملی, سیداصلان   +4 more
core