Results 201 to 210 of about 55,883 (307)

Effects of Pulsed Electromagnetic Field Application on Glucose Metabolism in Rats. [PDF]

Bioelectromagnetics
Gencer H, Bilgin HM, Akpolat V, Erkan REC, Alabalık U, Baksi N, Akpolat İ.   +6 more
europepmc   +1 more source

The cold‐water immersion recovery–adaptation paradox: Reconciling acute parasympathetic and analgesic benefits with chronic hypertrophy attenuation

Experimental Physiology, EarlyView.
Abstract Cold‐water immersion (CWI) is among the most widely used post‐exercise recovery modalities in elite sport and clinical rehabilitation, yet a fundamental paradox now emerges from the evidence: the same protocols that accelerate parasympathetic reactivation and reduce perceived muscle soreness also suppress the molecular and cellular machinery ...
Jose Francisco Tornero‐Aguilera, Jose Lozano‐Meca, Miguel López‐Moreno, Edgar Simón Sancho‐Haro, Mario Muñoz‐López, Eneko Baz‐Valle, José Francisco López‐Gil, Rodrigo Yáñez‐Sepúlveda, Vicente Javier Clemente‐Suárez   +8 more
wiley   +1 more source

Targeting Sirtuins in Thyroid Cancer: Mechanisms, Drug Development, and Emerging Roles in Tumor Immunity and Ferroptosis. [PDF]

Cancers (Basel)
Cho KJ, Seo JH, Kwon H, Lee SJ, Hah YS, Park JJ.   +5 more
europepmc   +1 more source

Discovery of Forvisirvat (DS-7830a/SP-624), a Brain-Penetrant Sirtuin 6 Activator Derived from Griseofulvin with Antidepressant-Like Effects. [PDF]

ACS Med Chem Lett
Ogawa Y, Saito K, Nakajima K, Iwamoto O, Aoki K, Makino M, Tanaka S, Kurikawa N, Michishita-Kioi E, Nagata S, Fujita Y, Sasaki M, Kasahara A, Yasumatsu I, Hirasawa M, Saitoh W.   +15 more
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

SIRT6 signaling as an underexplored mechanistic node in nanoformulation-based neuroinflammation therapy for Alzheimer's disease. [PDF]

Alzheimers Dement (N Y)
Mancy AS.
europepmc   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

A novel framework for studying human aging: trophoblast stem cell-syncytiotrophoblast platform as a physiologically relevant and accelerated model of cellular aging. [PDF]

Life Med
Zhang Q, Lee EPW, Lin B, Tam TTKK, Feng Z, Liu P.   +5 more
europepmc   +1 more source

Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐eight trained males completed 8 weeks of supervised indoor cycling training, receiving post‐exercise and pre‐sleep ketone monoester (KE, n = 14) or isocaloric placebo (CON, n = 14). Both groups improved 30 min time‐trial performance with training, but KE achieved a 4% higher power output than CON at the end of the training
Ruben Robberechts, Youri Bekhuis, Myrthe Stalmans, Wout Lauriks, Martijn Kusters, Karim Taha, Thomas Rosseel, Guido Claessen, Chiel Poffé   +8 more
wiley   +1 more source