Results 221 to 230 of about 70,332 (311)

Candidate biomarker identification for blood stasis syndrome among coronary artery disease patients using the Olink proteomics platform. [PDF]

J Tradit Chin Med
Hongzheng LI, Guosheng L, Yuxuan P, Alexey Viktorovich C, Wenwen Y, Jie W, Jieming LU, Feifei L, Ruotong YU, Yue W, Zhiru Z, Aimei LU, Peng LI, Aling S, Linzi L, Hua QU, Changgeng FU.   +16 more
europepmc   +1 more source

Clinical Outcomes and Correlation With Biochemical Control in Hydroxocobalamin‐Treated Patients With Early‐Onset Cobalamin C Disease

JIMD Reports, Volume 67, Issue 3, May 2026.
ABSTRACT Cobalamin C (cblC) disease is the most common disorder of Vitamin B12 activation. The early‐onset form presents within the first few months of life, with some patients identified through newborn screening (NBS). However, despite early detection and optimal treatment, patient outcomes remain poor, with intellectual impairment and progressive ...
Arthavan Selvanathan, Ashley Hertzog, Jacqui Russell, Rosie Junek, Carolyn Ellaway, Kate Lichkus, Adviye Ayper Tolun, Kaustuv Bhattacharya   +7 more
wiley   +1 more source

SIRTUIN 1 AND SIRTUIN 3: PHYSIOLOGICAL

PHYSIOLOGICAL REVIEWS, 2013
Ruben Nogueiras, Kirk M. Habegger, Nilika Chaudhary, Brian Finan, Alexander S. Banks   +4 more
openaire  

RNA Modifications: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao, Tingwen Xiang, Chuan Yang, Xiaohua Wang, Gang Huang, Fei Luo, Zhao Xie, Yueqi Chen   +7 more
wiley   +1 more source

Evaluation of Sirtuin 1 (SIRT1) and Sirtuin 3 (SIRT3) in serum and cerebrospinal fluid following fatal traumatic brain injury. [PDF]

Int J Legal Med
Poniatowski ŁA, Siwińska A, Kwiatkowska M, Olczak M.   +3 more
europepmc   +1 more source

Sirtuins and regulatory miRNAs as epigenetic determinants of empagliflozin-mediated recovery after acute myocardial infarction. [PDF]

Cardiovasc Diabetol
Nowak-Szwed A, Eyileten C, Wicik Z, Ahmadova S, Palatini J, Siller-Matula J, von Lewinski D, Sourij H, Postula M.   +8 more
europepmc   +1 more source

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

The deacetylase Sir2 is the primary sensor driving transcriptional changes in response to low NAD+ in the yeast Kluyveromyces lactis. [PDF]

Genetics
Acharjee M, Humphrey K, Lactaoen V, Karageorgiou C, Liu B, Gokcumen O, Rusche LN.   +6 more
europepmc   +1 more source

The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging

Aging Cell, Volume 25, Issue 5, May 2026.
We revealed the pathophysiological significance and therapeutic potential of adipocyte mitochondrial NAD transporter, namely solute carrier family 25 member 51 (SLC25A51), in age‐associated metabolic diseases, particularly adipose tissue mitochondrial function, obesity, and insulin resistance, by analyzing adipocyte‐specific Slc25a51 knockout (ASKO ...
Daiki Kojima, Keisuke Yaku, Shotaro Kosugi, Ryunosuke Mitsuno, Kenji Kaneko, Yoshinaga Kawano, Akihito Hishikawa, Seiya Mizuno, Manami Katoh, Akiko Satoh, Shinya Toyokuni, Tatsuhiko Azegami, Kenichiro Kinouchi, Shintaro Yamaguchi, Hiroshi Itoh, Takeshi Kanda, Toshimasa Yamauchi, Takashi Nakagawa, Kaori Hayashi, Jun Yoshino   +19 more
wiley   +1 more source

Mitochondrial sirtuins sir-2.2 and sir-2.3 regulate lifespan in C. elegans. [PDF]

Genetics
Chang SM, Franklin LP, Sattar S, Moro CA, DeGennaro MV, LaGanke NG, Hanna-Rose W.   +6 more
europepmc   +1 more source