Obesity Reviews, EarlyView.ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang +4 more
wiley +1 more source
Advances in sirtuin research in lung diseases (Review). [PDF]
Int J Mol MedXi S, Chen W, Li X, Wang Y, Ke Y.
europepmc +1 more source
Sirtuin modulators: a review of patents from 2020 to 2024
Introduction: Sirtuins have gained significant prominence in scientific research due to their involvement in a wide array of biological processes, including DNA repair, genome stability, transcription modulation, and signal transduction. Dysregulation of
Mai, Antonello +3 more
core +1 more source
Oxidative Stress–Driven Alterations in FoxO‐1 and MMP‐9 Activity in Smoking‐Associated Periodontitis
Oral Diseases, EarlyView.ABSTRACT Objectives Smoking disrupts oxidative balance and is a major risk factor for periodontitis. Forkhead box protein O‐1 (FoxO‐1) regulates antioxidant defense, yet its contribution to smoking‐associated periodontal breakdown is unclear. This cross‐sectional case–control study assessed reactive oxygen species (ROS), matrix metalloproteinase‐9 (MMP‐
Fatma Oner +4 more
wiley +1 more source
Sirtuins at the Interface of Glucose Metabolism, Diabetes, and Heart Failure: Metabolic Sensing in Cardiometabolic Disease. [PDF]
Int J Mol SciKrekora J +3 more
europepmc +1 more source
Protection against age-related neuronal frailty by sirtuin 1 enhancement
, 2014 Trabajo presentado al 8th Forum of Neuroscience (FENS) celebrado en Barcelona del 14 al 18 de julio de 2012.In aging and in the diseases associated with the elderly occurs a progressive cognitive loss caused by deteriorating brain function.
Sanfeliu, Coral +5 more
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Altered Embryonic SIRT6 and SIRT7 Expression Is Associated with Impaired Developmental Competence and Oocyte-Dependent Embryo Quality in Embryos Derived from Subfertile Males. [PDF]
Int J Mol SciKowalczyk A +9 more
europepmc +1 more source
Periodontology 2000, EarlyView.Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng +4 more
wiley +1 more source
Short-Term Effects of Intradialytic Hypoxemia on Plasma Markers of Hypoxia. [PDF]
Int J Mol SciKorzycka J +2 more
europepmc +1 more source
Determining the Conservation and Metabolic Role of Sirtuin Lipoamidase Activity
, 2017 Lipoic acid is a necessary cofactor for several evolutionarily-conserved metabolic enzymes, including the pyruvate dehydrogenase complex (PDH) and alpha-ketoglutarate dehydrogenase complex (KDH).
Snowden, Caroline
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