Results 251 to 260 of about 84,834 (402)

Enviromimetics: From exercise mimetics to cognitomimetics in the quest for enhanced brain health and cognition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A schematic diagram outlining the concept of enviromimetics, and the subclasses of exercise mimetics, epimimetics and cognitomimetics. The rationale is that environmental stimulation and lifestyle factors, including physical activity and cognitive stimulation, have shown beneficial effects across a range of human conditions ...
Anthony J. Hannan
wiley   +1 more source

Mitochondrial sirtuins sir-2.2 and sir-2.3 regulate lifespan in C. elegans. [PDF]

open access: yesGenetics
Chang SM   +6 more
europepmc   +1 more source

Are sirtuins viable targets for improving healthspan and lifespan? [PDF]

open access: green, 2012
Joseph A. Baur   +4 more
openalex   +1 more source

Early sensorimotor restriction in rats induces age‐dependent mitochondrial alterations in skeletal muscles and brain structures

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Mélanie Van Gaever   +4 more
wiley   +1 more source

Pregnancy shifts endothelial progenitor cell morphology and function: Role of metabolism, pro‐inflammatory cytokines and fetal sex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We recruited non‐pregnant women (NP), women in early pregnancy (EP) and late pregnancy (LP) for isolation of endothelial colony forming cells (ECFCs) via density gradient centrifugation. Plasma supernatant was collected for analysis of markers of glucose and lipid metabolism (fasting glucose, triglycerides, cholesterol, low ...
Marie‐Therese Weiser‐Fuchs   +14 more
wiley   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Cyclin-Dependent Kinase 5–Mediated Hyperphosphorylation of Sirtuin-1 Contributes to the Development of Endothelial Senescence and Atherosclerosis [PDF]

open access: bronze, 2012
Bo Bai   +7 more
openalex   +1 more source

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