Results 11 to 20 of about 23,914,328 (286)
Sirtuin 1 Levels in Recurrent Implantation Failure [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2017 Sirtuin 1 has an important role in cellular processes, including apoptosis and cellular stress. The purpose of this study was to assess serum sirtuin 1 levels in women with recurrent implantation failure (RIF).
Yaprak Engin-Ustun +8 more
doaj +10 more sources
Sirtuin 1: A Dilemma in Transplantation [PDF]
Journal of Transplantation, 2020 Sirtuin 1, a member of sirtuin family of histone deacetylase enzymes, has been implicated in a variety of physiologic and pathologic events, including energy metabolism, cell survival, and age-related alterations.
Sara Assadiasl +4 more
doaj +3 more sources
Comment on “Renal Protective Effect of Sirtuin 1” [PDF]
Journal of Diabetes Research, 2015 I read the review article written by Dong et al. [1] regarding the renal effects of sirtuin 1 with great interest. The authors described the harmful effects of advanced glycation end products on podocyte apoptosis via increasing Bcl-2 protein secondary to forkhead box O4 (FOXO4) acetylation in diabetes mellitus according to Chung et al.' findings ...
Kultigin Turkmen
doaj +5 more sources
Renal Protective Effect of Sirtuin 1 [PDF]
Journal of Diabetes Research, 2014 Silent information regulator 2 (Sir2) is a nicotinamide adenine dinucleotide- (NAD+-) dependent deacetylase. The homology of SIRT1 and Sir2 has been extensively studied.
Yi-jun Dong +7 more
doaj +4 more sources
Sleep, Sirtuin 1 and Alzheimer’s disease: A review
Aging Brain, 2022 Sleep plays a major role in brain health, and cognition. Disrupted sleep is a well-described symptom of Alzheimer’s disease (AD). However, accumulating evidence suggests suboptimal sleep also increases AD risk. The deacetylase Sirtuin 1 (Sirt 1), encoded
Mehrane Mehramiz +3 more
doaj +4 more sources
The Versatility of Sirtuin-1 in Endocrinology and Immunology [PDF]
Frontiers in Cell and Developmental Biology, 2020 Sirtuins belong to the class III family of NAD-dependent histone deacetylases (HDAC) and are involved in diverse physiological processes that range from regulation of metabolism and endocrine function to coordination of immunity and cellular responses to
F. Rasha +6 more
semanticscholar +5 more sources
Sirtuin-1 and Its Relevance in Vascular Calcification [PDF]
International Journal of Molecular Sciences, 2020 Vascular calcification (VC) is highly associated with cardiovascular disease and all-cause mortality in patients with chronic kidney disease. Dysregulation of endothelial cells and vascular smooth muscle cells (VSMCs) is related to VC.
Chien-Lin Lu +8 more
semanticscholar +3 more sources
Sirtuin 1 Expression in Canine Mammary Tumors: A Pilot Study [PDF]
Animals, 2023 Sirtuin 1 (SIRT1) is a protein involved in aging, cell protection, and energy metabolism in mammals. Recently, SIRT1 has been intensively studied in medical oncology, but the role of SIRT1 is still controversial, as it has been proposed as both an ...
Mariafrancesca Sgadari +4 more
doaj +2 more sources
Sirtuin 1 and Hormonal Regulations in Aging
Applied SciencesAging affects the structure and functions of all organs and systems in the organism. In the elderly, significant changes in hormonal levels are observed.
Milena Keremidarska-Markova +5 more
doaj +2 more sources
Role of sirtuin-1 in diabetic nephropathy [PDF]
Journal of Molecular Medicine, 2019 Diabetic nephropathy (DN) is a research priority for scientists around the world because of its high prevalence and poor prognosis. Although several mechanisms have been shown to be involved in its pathogenesis and many useful drugs have been developed ...
Wan-ning Wang +4 more
semanticscholar +4 more sources