Results 11 to 20 of about 65,569 (207)

Role of acetylation in nonalcoholic fatty liver disease: a focus on SIRT1 and SIRT3

Exploration of Medicine, 2020
Nonalcoholic fatty liver disease (NAFLD) has become the most prevalent liver chronic disease worldwide. The pathogenesis of NAFLD is complex and involves many metabolic enzymes and multiple pathways.
Fatiha Nassir
doaj   +1 more source

(+)-Catechin & Proanthocyanidin Fraction of Uncaria gambir Roxb. Improve Adipocytes Differentiation & Glucose Uptake of 3T3-L1 Cells Via Sirtuin-1, Peroxisome Proliferator-Activated Receptor γ (PPAR γ), Glucose Transporter Type 4 (GLUT-4) Expressions [PDF]

Advanced Pharmaceutical Bulletin, 2020
Purpose: To improve adipocytes differentiation & glucose uptake activity of 3T3-L1 cells through sirtuin-1, peroxisome proliferator-activated receptor γ (PPAR γ), glucose transporter type 4 (GLUT-4) of (+)-catechin & proanthocyanidin fraction Uncaria ...
Silvy Arundita, Friardi Ismed, Rauza Sukma Rita, Deddi Prima Putra   +3 more
doaj   +1 more source

Elucidation of the Mechanism Underlying the Anti-Inflammatory Properties of (S)-(+)-Carvone Identifies a Novel Class of Sirtuin-1 Activators in a Murine Macrophage Cell Line

Biomedicines, 2021
The signaling pathways involved in age-related inflammation are increasingly recognized as targets for the development of preventive and therapeutic strategies.
Cátia Sousa, Bruno Miguel Neves, Alcino Jorge Leitão, Alexandrina Ferreira Mendes   +3 more
doaj   +1 more source

Sirtuin 1 in Host Defense during Infection

Cells, 2022
Sirtuins (SIRTs) are members of the class III histone deacetylase family and epigenetically control multiple target genes to modulate diverse biological responses in cells. Among the SIRTs, SIRT1 is the most well-studied, with a role in the modulation of
Jin Kyung Kim, Prashanta Silwal, Eun-Kyeong Jo   +2 more
doaj   +1 more source

Sirtuin 1: A Dilemma in Transplantation

Journal of Transplantation, 2020
Sirtuin 1, a member of sirtuin family of histone deacetylase enzymes, has been implicated in a variety of physiologic and pathologic events, including energy metabolism, cell survival, and age-related alterations.
Sara Assadiasl, Nuala Mooney, Bahareh Mohebbi, Yousef Fatahi, Narjes Soleimanifar   +4 more
doaj   +1 more source

Sirtuin 1 Levels in Recurrent Implantation Failure [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2017
Sirtuin 1 has an important role in cellular processes, including apoptosis and cellular stress. The purpose of this study was to assess serum sirtuin 1 levels in women with recurrent implantation failure (RIF).
Yaprak Engin-Ustun, A. Seval Ozgu-Erdinc, Emel Kiyak Caglayan, Cavidan Gulerman, Esma Sarikaya, Ayla Aktulay, Canan Demirtas, Salim Erkaya, Nafiye Yilmaz   +8 more
doaj   +1 more source

Association of sirtuin-1 and vascular endothelial growth factor expression with tumor progression and poor prognosis in liposarcoma

Journal of International Medical Research, 2020
Objectives A relationship exists between sirtuin-1 expression and growth and survival of malignant tumors. This study aimed to investigate the prognostic value of sirtuin-1 and vascular endothelial growth factor (VEGF) expression in patients with ...
Hongzeng Wu, Qianqian Zhang, Yi Zhao, Fengzhou Xu, Jinming Zhang, Hongyan He, Xu Wang, Helin Feng   +7 more
doaj   +1 more source

Hsa-miR-217 Inhibits the Proliferation, Migration, and Invasion in Non-small Cell Lung Cancer Cells Via Targeting SIRT1 and P53/KAI1 Signaling

Balkan Medical Journal, 2020
Background: Brain metastasis is a major cause of cancer death in patients with lung cancer. Sirtuin 1 and hsa-miR-217 have been identified to mediate the development of non-small cell lung cancer.
Wenxia Jiang, Likun Hou, Juan Wei, Yifeng Du, Yan Zhao, Xue Deng, Xiangdong Lin   +6 more
doaj   +1 more source

Pengaruh Pemberian Mesenchymal Stem Cells Wharton's Jelly terhadap Ekspresi Gen Sirtuin 1 pada Tikus Model Alzheimer

Jurnal Kesehatan Andalas, 2023
Mesenchymal Stem Cells Wharton's Jelly (MSC-WJ) has become a new hope for Alzheimer's disease due to its capability to suppress Amyloid-beta (Aβ) plaques formation.
Havina Nurul Aizah, Amel Yanis, Hirowati Ali, Tofrizal Tofrizal, Cimi Ilmiawati, Dessy Arisanty   +5 more
doaj   +1 more source

Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer [PDF]

, 2013
Histone variants seem to play a major role in gene expression regulation. In prostate cancer, H2A.Z and its acetylated form are implicated in oncogenes’ upregulation.
Amado, Francisco, Baptista, Tiago, Costa, Natália R., Costa-Pinheiro, Pedro, Henrique, Rui, Jerónimo, Carmen, Oliveira, Ana Isabel, Pinho dos Santos Graça, Maria Inês, Sousa, Elsa Joana   +8 more
core   +2 more sources