Results 231 to 240 of about 18,502 (257)
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A Review on SIRtuins in Diabetes
Current Pharmaceutical Design, 2017Type-2 Diabetes is a long lasting disease characterized by high glucose concentration in the blood due to insulin resistance. One of the recent treatment strategies is using activators against SIRT-1, which has been in clinical trials. Hence, it is necessary to know the effects of the SIRT-1 modulators against various metabolic pathways.Many cellular ...
R, Aditya +4 more
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Sirtuins' modulation of autophagy
Journal of Cellular Physiology, 2013AbstractThe sirtuin family of class III histone deacetylases has been extensively implicated in modulating a myriad of cellular processes, including energy metabolism, stress response, cell/tissue survival and malignancy. Recent studies have also identified multifaceted roles for Sirt1 and Sirt2 in the regulation of autophagy.
Fanny, Ng, Bor Luen, Tang
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Sirtuins and the prevention of immunosenescence
2021Aging of hematopoietic stem cells (HSCs) has been largely described as one underlying cause of senescence of the immune-hematopoietic system (immunosenescence). A set of well-defined hallmarks characterizes aged HSCs contributing to unbalanced hematopoiesis and aging-associated functional alterations of both branches of the immune system.
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A comprehensive review of Sirtuins: With a major focus on redox homeostasis and metabolism
Life Sciences, 2021Fatemeh Rezaei Kahmini +1 more
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Mitochondrial sirtuins, metabolism, and aging
Journal of Genetics and Genomics, 2022Guang-Hui Liu, Jing Qu, Zhejun Ji
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Mitochondrial Sirtuins in Parkinson’s Disease
Neurochemical Research, 2022Huaijun Tu, Ling He
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The Role of Sirtuins in Kidney Diseases
International Journal of Molecular Sciences, 2020Yu Ah Hong, Gangjee Ko
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Sirtuins as regulators of metabolism and healthspan
Nature Reviews Molecular Cell Biology, 2012Riekelt H Houtkooper +2 more
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