Bacteriophage P1 encodes a site-specific recombination system that consists of a site (loxP) at which recombination occurs and a gene, cre, whose protein product is essential for recombination.
K. Abremski, R. Hoess
semanticscholar +1 more source
Toward Memory in a DNA Brush: Site-Specific Recombination Responsive to Polymer Density, Orientation, and Conformation. [PDF]
Avidan N, Levy M, Daube SS, Bar-Ziv RH.
europepmc +1 more source
Conversion of a telomere resolvase into a Cre-like site-specific recombinase.
Hairpin telomere resolvases are a unique family of enzymes involved in producing the hairpin (hp) telomeres of bacterial organisms and phages that possess linear DNA's terminated by hp telomeres.
Shu Hui Huang +2 more
doaj +1 more source
Marker-Free Genome Engineering in Amycolatopsis Using the pSAM2 Site-Specific Recombination System. [PDF]
Santos LDF +3 more
europepmc +1 more source
Potential Mobilization of mcr-10 by an Integrative Mobile Element via Site-Specific Recombination in Cronobacter sakazakii. [PDF]
Yang J +5 more
europepmc +1 more source
Xer Site-specific Recombination [PDF]
Ian Grainge, David J. Sherratt
openaire +1 more source
One-step Cre-loxP organism creation by TAx9
The creation of organisms with Cre-loxP conditional gene recombination systems often faces challenges, particularly when creating the initial (F0) generation with both a Cre recombinase and a DNA site flanked by loxP elements (floxed site).
Martin Miguel Casco-Robles +8 more
doaj +1 more source
Site-Specific Recombination - How Simple DNA Inversions Produce Complex Phenotypic Heterogeneity in Bacterial Populations. [PDF]
Trzilova D, Tamayo R.
europepmc +1 more source
Site-specific recombination caught in the act
AbstractThe recently determined crystal structure of Cre recombinase from bacteriophage P1, bound to its target DNA, sheds considerable light on the mechanism underlying a major type of site-specific DNA recombination, and shows how strand exchange can be achieved without reorganisation of the protein complex.
openaire +2 more sources
Ligand-Controlled Site-Specific Recombination in Zebrafish
Cre-mediated site-specific recombination has emerged as an indispensable tool for the precise manipulation of genomes allowing lineage-tracing studies, temporal and spatial misexpressions, and in particular the generation of conditional knockout alleles.
Chekuru, Avinash +3 more
openaire +4 more sources

