Results 1 to 10 of about 2,662,527 (408)

Exercise metabolism and adaptation in skeletal muscle

Nature Reviews Molecular Cell Biology, 2023
Jonathon A B Smith, Kevin A Murach, Kenneth A. Dyar   +2 more
exaly   +2 more sources

Mitochondrial dysfunction: roles in skeletal muscle atrophy

Journal of Translational Medicine, 2023
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle health, and damage to mitochondria can lead to a series of pathophysiological changes.
Xin Chen, Yi Ji, Ruiqi Liu, Xucheng Zhu, Kexin Wang, Xiaoming Yang, Boya Liu, Zihui Gao, Yan Huang, Yuntian Shen, Hua Liu, Hualin Sun   +11 more
semanticscholar   +1 more source

A research update: Significance of cytokine storm and diaphragm in COVID-19

Current Research in Pharmacology and Drug Discovery, 2021
Emerging research on severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) shows that it is spreading to multiple organs in addition to the respiratory system.
Ashwani Mittal, Anita Dua, Sanjeev Gupta, Elisha Injeti   +3 more
doaj   +1 more source

Skeletal muscle alterations in patients with acute Covid‐19 and post‐acute sequelae of Covid‐19

Journal of Cachexia, Sarcopenia and Muscle, 2022
Skeletal muscle‐related symptoms are common in both acute coronavirus disease (Covid)‐19 and post‐acute sequelae of Covid‐19 (PASC). In this narrative review, we discuss cellular and molecular pathways that are affected and consider these in regard to ...
Madu N Soares, Moritz Eggelbusch, E. Naddaf, K. Gerrits, M. Schaaf, B. Borst, W. Wiersinga, M. Vugt, P. Weijs, A. Murray, R. C. Wüst   +10 more
semanticscholar   +1 more source

Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study

Journal of the International Society of Sports Nutrition, 2021
Background Acute capsaicinoid and capsinoid supplementation has endurance and resistance exercise benefits; however, if these short-term performance benefits translate into chronic benefits when combined with resistance training is currently unknown ...
Vilton Emanoel Lopes de Moura e Silva, Jason Michael Cholewa, Ralf Jäger, Nelo Eidy Zanchi, Marcelo Conrado de Freitas, Rayane Carvalho de Moura, Esmeralda Maria Lustosa Barros, Barbara Moura Antunes, Erico Chagas Caperuto, Sergio Luiz Galan Ribeiro, Fabio Santos Lira, Marcos Antônio Pereira dos Santos, Fabrício Eduardo Rossi   +12 more
doaj   +1 more source

Perspectives on skeletal muscle stem cells

Nature Communications, 2021
Skeletal muscle has remarkable regeneration capabilities, mainly due to its resident muscle stem cells (MuSCs). In this review, we introduce recently developed technologies and the mechanistic insights they provide to the understanding of MuSC biology ...
F. Relaix, M. Bencze, M. Borok, A. Der Vartanian, F. Gattazzo, D. Mademtzoglou, S. Pérez-Díaz, A. Prola, P. C. Reyes-Fernandez, A. Rotini, Taglietti   +10 more
semanticscholar   +1 more source

Dose-response of acute capsiate supplementation on muscle endurance performance during CrossFit® in trained men: A randomized, crossover and double-blind study

Human Nutrition & Metabolism, 2023
Objectives: This study aimed to verify the acute effect of Capsiate (CAP) on muscle endurance resistance training during CrossFit® and to compare the effects of two acute doses of CAP supplementation (12 vs.
Marcelo da Silva Mesquita Oliveira, Paulo Renan Macêdo, Nathanael Leal Santana, Flávio Antônio de Sousa Nunes, Jason Michael Cholewa, Priscila Almeida Queiroz Rossi, Ahecio Kleber Araújo Brito, Nelo E. Zanchi, Fabrício Eduardo Rossi   +8 more
doaj   +1 more source

Pharmacological inhibition of lipolysis prevents adverse metabolic outcomes during glucocorticoid administration

Molecular Metabolism, 2023
Objective: Glucocorticoids are one of the most commonly prescribed classes of anti-inflammatory drugs; however, chronic treatment promotes iatrogenic (drug-induced) diabetes.
Melissa A. Linden, Susan J. Burke, Humza A. Pirzadah, Tai-Yu Huang, Heidi M. Batdorf, Walid K. Mohammed, Katarina A. Jones, Sujoy Ghosh, Shawn R. Campagna, J. Jason Collier, Robert C. Noland   +10 more
doaj   +1 more source

Extracellular matrix: an important regulator of cell functions and skeletal muscle development

Cell & Bioscience, 2021
Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which is of great significance to tissue development. ECM in muscle fiber niche consists of three layers: the epimysium, the perimysium, and the endomysium (basal ...
Weiya Zhang, Yuan-yuan Liu, Hong Zhang
semanticscholar   +1 more source

Low immunogenicity of LNP allows repeated administrations of CRISPR-Cas9 mRNA into skeletal muscle in mice

Nature Communications, 2021
Genome editing therapy for Duchenne muscular dystrophy (DMD) holds great promise, however, one major obstacle is delivery of the CRISPR-Cas9/sgRNA system to skeletal muscle tissues.
E. Kenjo, Hiroyuki Hozumi, Yukimasa Makita, Kumiko A. Iwabuchi, N. Fujimoto, Satoru Matsumoto, Maya Kimura, Y. Amano, Masataka Ifuku, Youichi Naoe, Naoto Inukai, A. Hotta   +11 more
semanticscholar   +1 more source