Results 1 to 10 of about 879,292 (313)

HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses [PDF]

Skeletal Muscle, 2018
Background Denervation triggers numerous molecular responses in skeletal muscle, including the activation of catabolic pathways and oxidative stress, leading to progressive muscle atrophy.
Eva Pigna, Alessandra Renzini, Emanuela Greco, Elena Simonazzi, Stefania Fulle, Rosa Mancinelli, Viviana Moresi, Sergio Adamo   +7 more
doaj   +3 more sources

Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study

Journal of the International Society of Sports Nutrition, 2021
Background Acute capsaicinoid and capsinoid supplementation has endurance and resistance exercise benefits; however, if these short-term performance benefits translate into chronic benefits when combined with resistance training is currently unknown ...
Vilton Emanoel Lopes de Moura e Silva, Jason Michael Cholewa, Ralf Jäger, Nelo Eidy Zanchi, Marcelo Conrado de Freitas, Rayane Carvalho de Moura, Esmeralda Maria Lustosa Barros, Barbara Moura Antunes, Erico Chagas Caperuto, Sergio Luiz Galan Ribeiro, Fabio Santos Lira, Marcos Antônio Pereira dos Santos, Fabrício Eduardo Rossi   +12 more
doaj   +1 more source

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering [PDF]

, 2018
Summary: Generating human skeletal muscle models is instrumental for investigating muscle pathology and therapy. Here, we report the generation of three-dimensional (3D) artificial skeletal muscle tissue from human pluripotent stem cells, including ...
Cappellari, O, Duchen, M R, Eschenhagen, T, Ferrari, G, Henderson, A B H, Khedr, M, Kotiadis, V N, Maffioletti, S M, Mannhardt, I, Mitchell, J S, Moyle, L A, Patani, R, Pinton, L, Ragazzi, M, Sarcar, S, Steele-Stallard, H, Tedesco, F S, Tyzack, G E, Wang, W, Wells, D J, Wells, K E, Zammit, P S   +21 more
core   +8 more sources

Meeting report: the 2021 FSHD International Research Congress

Skeletal Muscle, 2022
Facioscapulohumeral muscular dystrophy (FSHD) is the second most common genetic myopathy, characterized by slowly progressing and highly heterogeneous muscle wasting with a typical onset in the late teens/early adulthood [1]. Although the etiology of the
Sujatha Jagannathan, Jessica C. de Greef, Lawrence J. Hayward, Kyoko Yokomori, Davide Gabellini, Karlien Mul, Sabrina Sacconi, Jamshid Arjomand, June Kinoshita, Scott Q. Harper   +9 more
doaj   +1 more source

Developing cardiac and skeletal muscle share fast-skeletal myosin heavy chain and cardiac troponin-I expression [PDF]

, 2012
Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate into fast skeletal muscle specific myosin heavy chain (sk-fMHC) and cardiac specific troponin-I (cTn-I) positive cells sustaining recipient myocardial ...
A Du, B Camoretti-Mercado, B Messner, Bradley B. Keller, C Cognard, CJ Sutherland, CS Rutland, D Pette, D Sassoon, F Fougerousse, F Pedrosa-Domellof, FS Apple, GE Lyons, H Oshima, Jason Tchao, JG Jacot, Johnny Huard, K Tobita, KC Clause, Kelly C. Clause, Kimimasa Tobita, L Saggin, L Saggin, Li J. Liu, LJ Sweeney, M Bahler, M Kawashima, M Okada, M Yasuda, Marie Jose Goumans, Mary C. Powell, N Hamalainen, R Di Lisi, RJ Solaro, S Fredericks, S Sartore, S Schiaffino, S Siedner, SK Bortolotto, V Haufe   +39 more
core   +7 more sources

Denervation does not induce muscle atrophy through oxidative stress [PDF]

, 2017
Denervation leads to the activation of the catabolic pathways, such as the ubiquitin-proteasome and autophagy, resulting in skeletal muscle atrophy and weakness.
Adamo, Sergio, Bellezza, Ilaria, Fulle, Stefania, Greco, Emanuela, Grottelli, Silvia, Mancinelli, Rosa, Minelli, Alba, Moresi, Viviana, Morozzi, Giulio, Pigna, Eva, Rotini, Alessio   +10 more
core   +2 more sources

The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]

, 2015
The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio, C. S. Mosteiro, D. l. Beiroa, F. F. Casanueva, I. Santos Zas, J. E. Viñuela, J. González Sánchez, J. M. Renaud, J. P. Camiña, J. Señarís, MORESI, Viviana, R. Gallego, R. Nogueiras, T. García Caballero, U. Gurriarán Rodríguez, W. Lin, Y. Pazos   +16 more
core   +1 more source

Transcriptional profiling reveals extraordinary diversity among skeletal muscle tissues [PDF]

, 2018
Skeletal muscle comprises a family of diverse tissues with highly specialized functions. Many acquired diseases, including HIV and COPD, affect specific muscles while sparing others.
Andrade, Francisco, Douglas, Collin M, Esser, Karyn A, Gong, Ming C, Gutierrez-Monreal, Miguel A, Hoffmann, Christy, Hughes, Laura D, Hughes, Michael E, Lahens, Nicholas F, Lewis, Scott A, Li, Jiajia, Riley, Lance A, Terry, Erin E, Wallace, Matthew J, Zhang, Xiping   +14 more
core   +4 more sources

Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage [PDF]

, 2020
Glycogenin is considered to be an essential primer for glycogen biosynthesis. Nevertheless, patients with glycogenin-1 deficiency due to biallelic GYG1 (NM_004130.3) mutations can store glycogen in muscle.
Dellgren, Göran, Glamuzina, Emma, Hedberg-Oldfors, Carola, Hernandez-Lain, Aurelio, Kornblum, Cornelia, Oldfors, Anders, Roach, Peter, Sandstedt, Joakim, Tasca, Giorgio, Thomsen, Christer, Visuttijai, Kittichate   +10 more
core   +1 more source

Redox proteomic analysis of the gastrocnemius muscle from adult and old mice

Data in Brief, 2015
The data provides information in support of the research article, “Differential Cysteine Labeling and Global Label-Free Proteomics Reveals an Altered Metabolic State in Skeletal Muscle Aging”, Journal of Proteome Research, 2014, 13 (11), 2008–21 [1]. Raw
Brian McDonagh, Giorgos K. Sakellariou, Neil T. Smith, Philip Brownridge, Malcolm J. Jackson   +4 more
doaj   +1 more source