Role of Skeletal Muscle in Insulin Resistance and Glucose Uptake.
Comprehensive Physiology, 2020 The skeletal muscle is the largest organ in the body, by mass. It is also the regulator of glucose homeostasis, responsible for 80% of postprandial glucose uptake from the circulation.
Karla E. Merz, D. Thurmond
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Prions in skeletal muscle [PDF]
Proceedings of the National Academy of Sciences, 2002 Considerable evidence argues that consumption of beef products from cattle infected with bovine spongiform encephalopathy (BSE) prions causes new variant Creutzfeldt–Jakob disease. In an effort to prevent new variant Creutzfeldt–Jakob disease, certain “specified offals,” including neural and lymphatic tissues, thought to contain high ...
BOSQUE PJ +6 more
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The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]
, 2015 The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio +16 more
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Transcriptional profiling reveals extraordinary diversity among skeletal muscle tissues [PDF]
, 2018 Skeletal muscle comprises a family of diverse tissues with highly specialized functions. Many acquired diseases, including HIV and COPD, affect specific muscles while sparing others.
Andrade, Francisco +14 more
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Enhancement of K+ conductance improves in vitro the contraction force of skeletal muscle in hypokalemic periodic paralysis [PDF]
, 1990 An abnormal ratio between Na+ and K+ conductances seems to be the cause for the depolarization and paralysis of skeletal muscle in primary hypokalemic periodic paralysis.
Ballanyi +19 more
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Single-cell transcriptional profiles in human skeletal muscle
Scientific Reports, 2020 Skeletal muscle is a heterogeneous tissue comprised of muscle fiber and mononuclear cell types that, in addition to movement, influences immunity, metabolism and cognition.
A. Rubenstein +12 more
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Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases [PDF]
, 2014 Physical inactivity is a predisposing factor for various disease states including obesity, cardiovascular disease, as well as for certain types of cancer. Regular endurance exercise mediates several beneficial effects such as increased energy expenditure
Handschin, Christoph +1 more
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Mechanism of increased risk of insulin resistance in aging skeletal muscle
Diabetology & Metabolic Syndrome, 2020 As age increases, the risk of developing type 2 diabetes increases, which is associated with senile skeletal muscle dysfunction. During skeletal muscle aging, mitochondrial dysfunction, intramyocellular lipid accumulation, increased inflammation ...
J. Shou, Pei-jie Chen, W. Xiao
semanticscholar +1 more source
Redox proteomic analysis of the gastrocnemius muscle from adult and old mice
Data in Brief, 2015 The data provides information in support of the research article, “Differential Cysteine Labeling and Global Label-Free Proteomics Reveals an Altered Metabolic State in Skeletal Muscle Aging”, Journal of Proteome Research, 2014, 13 (11), 2008–21 [1]. Raw
Brian McDonagh +4 more
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Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease [PDF]
, 2017 Atherosclerosis is a chronic inflammatory process that, in the presence of hyperlipidaemia, promotes the formation of atheromatous plaques in large vessels of the cardiovascular system.
Matsakas, Antonios, Sfyri, Peggy
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