Results 101 to 110 of about 1,143,192 (208)

Nitric oxide synthase in skeletal muscle fibres of patients with type 2 diabetes [PDF]

, 2012
Muscle-derived nitric oxide (NO) mediates fundamental physiological actions on skeletal muscle including glucose uptake into muscle cells. Recently, we have shown that the altered glucose metabolism in skeletal muscle of patients with type 2 diabetes ...
Karla Punkt, Volker Adams, Katharina Kandt, Matthias Blueher, Andreas Oberbach, Igor Buchwalow   +5 more
core  

Prevention of skeletal muscle wasting: disuse atrophy and sarcopenia [PDF]

, 2012
First paragraph: Skeletal muscle plays a considerable role in health and disease. Muscle mass is essential for health and survival and plays a major role in mobility as well as morbidity and mortality.
Brooks, Naomi, Naomi E., Myburgh, Kathryn H, Kathryn H.   +3 more
core   +1 more source

Capsaicin protects against atrophy in human skeletal muscle cells [PDF]

, 2014
Skeletal muscle atrophy occurs in many pathological conditions, e.g. AIDS, cancer, sepsis and starvation, and with increased age. There is currently no effective treatment to prevent or reverse this muscle wasting.
Kortzon, Evelina C
core  

KLF13 restrains Dll4‐muscular Notch2 axis to improve the muscle atrophy

Journal of Cachexia, Sarcopenia and Muscle
Background Muscle atrophy can cause muscle dysfunction and weakness. Krüppel‐like factor 13 (KLF13), a central regulator of cellular energy metabolism, is highly expressed in skeletal muscles and implicated in the pathogenesis of several diseases.
Shu Yang, Lijiao Xiong, Guangyan Yang, Jiaqing Xiang, Lixing Li, Lin Kang, Zhen Liang   +6 more
doaj   +1 more source

Extracellular vesicles derived from immobilization‐induced atrophic muscle of male mice contain distinct microRNA profiles and impact mRNA profiles in brain neurons

Physiological Reports
Muscle atrophy caused by inactivity leads to declines in multiple physiological functions, including brain function. Although skeletal muscle is known to secrete extracellular vesicles (EVs) such as exosomes, how inactivity‐induced muscle atrophy alters ...
Noriaki Kawanishi, Shuichi Machida, Katsuhiko Suzuki   +2 more
doaj   +1 more source

The slow sarco/endoplasmic reticulum Ca2+-ATPase declines independently of slow myosin in soleus muscle of diabetic rats [PDF]

, 2009
The sarcoplasmic reticulum Ca2+-ATPase (SERCA) isoforms are normally expressed in coordination with the corresponding myosin heavy chain (MyHC) isoforms in the fibers of skeletal muscle but this coordination is often disrupted in pathological conditions.
Rácz, Gábor, Zádor, Ernő, Vér, Ágota, Szabó, András   +3 more
core   +2 more sources

Berberine attenuates obesity-induced skeletal muscle atrophy via regulation of FUNDC1 in skeletal muscle of mice

Scientific Reports
Skeletal muscle atrophy is a complication of obesity, partially induced by impaired mitophagy. This study investigates whether Berberine(BBR) protects mice from obese skeletal muscle atrophy and the underlying molecular mechanism.
Yijie Wu, Yanhui Yang, Caixia Du, Xiaoyue Peng, Wenying Fan, Baocheng Chang, Chunyan Shan   +6 more
doaj   +1 more source

CONSTRUCTIVE TISSUE REMODELING BY EXTRACELLULAR MATRIX BIOSCAFFOLDS WITHIN THE AGING SKELETAL MUSCLE MICROENVIRONMENT [PDF]

, 2013
Adult mammalian skeletal muscle tissue retains inherent regenerative capability in response to injury. This regenerative response is contingent upon an activated progenitor cell population and a temporal transition from pro-inflammatory M1 to ...
Sicari, Brian
core  

Elevated levels of S100A8 and S100A9 exacerbate muscle mitochondrial fragmentation in sepsis-induced muscle atrophy

Communications Biology
Sepsis-induced skeletal muscle atrophy is common in septic patients with the increases risk of mortality and is associated with myocellular mitochondrial dysfunction. Nevertheless, the specific mechanism of sepsis muscle atrophy remains unclear.
Dongqin Huang, Yang Li, Yuqian Guo, Mengcao Weng, Hui Ye, Yan Zhang, Fei Lin, Kai Zhang, Xiangming Fang   +8 more
doaj   +1 more source

Apoptosis in skeletal muscle and its relevance to atrophy

World Journal of Gastroenterology, 2006
Apoptosis is necessary for maintaining the integrity of proliferative tissues, such as epithelial cells of the gastrointestinal system. The role of apoptosis in post mitotic tissues, such as skeletal muscle, is less well defined. Apoptosis during muscle atrophy occurs in both myonuclei and other muscle cell types.
openaire   +2 more sources