Results 201 to 210 of about 68,097 (255)

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

The Swedish National Pediatric Cataract Register (PECARE): Coexisting systemic disorders 2007–2023

Acta Ophthalmologica, EarlyView.
Abstract Purpose To analyse the frequency and type of coexisting systemic disorders in children operated on for cataract in Sweden. Methods Data were retrieved from the Swedish National Pediatric Cataract Register (PECARE) for children operated between January 1, 2007, and December 31, 2023 (n = 975), including follow‐ups at age 1, 2, 5 and 10 ...
David Wackerberg, Jenny Gyllén, Birgitte Haargaard, Alf Nyström, Arzu Karatepe Hashas, Anna Linnarsson Wiklund, Eric Trocmé, Ulrika Kjellström, Kristina Tornqvist, Gunilla Magnusson   +9 more
wiley   +1 more source

Role of IL-16 in age-related skeletal muscle atrophy: an integrated study. [PDF]

BMC Musculoskelet Disord
Fan W, Zhao Z, Wang L, Chu Q.
europepmc   +1 more source

Deciphering the mechanisms and effects of hyperglycemia on skeletal muscle atrophy. [PDF]

Metabol Open
Gaur K, Mohapatra L, Wal P, Parveen A, Kumar S, Gupta V.   +5 more
europepmc   +1 more source

Mechanotransduction and Skeletal Muscle Atrophy: The Interplay Between Focal Adhesions and Oxidative Stress. [PDF]

Int J Mol Sci
Kamal KY, Trombetta-Lima M.
europepmc   +1 more source

Stem cell therapy: A promising therapeutic approach for skeletal muscle atrophy. [PDF]

World J Stem Cells
Wang YJ, Chen ZH, Shen YT, Wang KX, Han YM, Zhang C, Yang XM, Chen BQ.   +7 more
europepmc   +1 more source

Studies on muscle atrophy in the mouse skeletal muscle

, 2000
openaire   +1 more source

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SnapShot: Skeletal muscle atrophy

Cell, 2022
Skeletal muscle size is highly plastic and sensitive to a variety of stimuli. Muscle atrophy occurs as the result of changes in multiple signaling pathways that regulate both protein synthesis and degradation. The signaling pathways that are activated or inhibited depend on the specific stimuli that are altered.
Leslie M, Baehr, David C, Hughes, David S, Waddell, Sue C, Bodine   +3 more
openaire   +2 more sources

Mechanisms of skeletal muscle atrophy

Current Opinion in Rheumatology, 2006
Recent clinical and mechanistic studies have shown that increased proteolysis is a major determinant of muscle wasting in numerous catabolic states and of alterations in myopathies or dystrophies. The implications of these observations for improving muscle mass and function are discussed.Several proteolytic systems (i.e. the ubiquitin-proteasome system,
Ventadour, Sophie, Attaix, Didier
openaire   +3 more sources

The molecular basis of skeletal muscle atrophy

American Journal of Physiology-Cell Physiology, 2004
Skeletal muscle atrophy attributable to muscular inactivity has significant adverse functional consequences. While the initiating physiological event leading to atrophy seems to be the loss of muscle tension and a good deal of the physiology of muscle atrophy has been characterized, little is known about the triggers or the molecular signaling events ...
Robert W, Jackman, Susan C, Kandarian
openaire   +2 more sources