Results 181 to 190 of about 1,205,857 (255)

Mechanical memory in aging: From adaptive sensing to pathological entrenchment

Interdisciplinary Medicine, EarlyView.
Mechanical memory in aging operates through four temporal tiers, from cytoskeletal remodeling to metabolic reprogramming. Aging disrupts this cascade through three distinct decoupling patterns: sensor degradation, conduction blockade, and execution failure, leading to irreversible pathological entrenchment across multiple organ systems.
Mingyang Huang, Xiaoyu Ma, Ruiqi Gao, Qichen Miao, Guoqing Wang, Ziyuan Liu, Kun Wang, Ming Luo   +7 more
wiley   +1 more source

The cGAS-STING pathway contributes to cisplatin-induced skeletal muscle atrophy through altered proteostasis and myogenic signaling. [PDF]

Cell Commun Signal
Liu X, Xu M, Wang H, Wang H, Wang H, Fang W, Li M, Huang J, Chen F, Wang H, Yu Y, Zhu L.   +11 more
europepmc   +1 more source

Association between augmented enteral protein and muscle mass attenuation in critically ill patients: A sub‐study of a cluster randomized crossover trial

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Critically ill patients experience muscle wasting, impacting recovery. The associations between augmented enteral protein and muscle mass, strength, physical function, and quality of life are uncertain. Methods We performed a sub‐study in adult TARGET Protein participants from two sites between 23/11/2022‐23/05/2023. Our exposure of
Matthew J. Summers, Elizabeth Viner Smith, Kate Hadley‐Brown, Amalia Karahalios, Tara D'Arcy, Imogen E. Asser, Mark P. Plummer, Terri Follett, Paul Young, Adam M. Deane, Lee‐anne S. Chapple   +10 more
wiley   +1 more source

Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review). [PDF]

Int J Mol Med
Dai W, Wu J, Ma X, Wu M, Li K, Gao H, Wang W, Xiao W.   +7 more
europepmc   +1 more source

Disease‐specific body composition patterns in children with cerebral palsy and spinal muscular atrophy

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Spinal muscular atrophy (SMA) and cerebral palsy (CP) are severe neurological conditions characterized by neurodegeneration and non‐progressive brain injury, respectively, both profoundly affecting the nutritional status in children.
Giulia Fiore, Sara Vizzuso, Ramona De Amicis, Barbara Borsani, Mireia Escudero‐Marín, Alessandra Mari, Francesca Destro, Hatim Azaryah, Chiara Mastella, Anna Mandelli, Laura Stabilini, Alessandra Bosetti, Francesca Izzo, Elena Zoia, Eleonora Bonaventura, Lorenzo Norsa, Davide Tonduti, Gloria Pelizzo, Cristina Campoy, Simona Bertoli, Gianvincenzo Zuccotti, Elvira Verduci   +21 more
wiley   +1 more source

LaminA/C-dependent cellular senescence signaling promotes skeletal muscle atrophy and abnormalities in Parkinson's disease. [PDF]

Cell Death Dis
Sharma J, Mondal S, Bisht KS, Biswas A, Panneerselvam L, Maiti TK, Mathew SJ.   +6 more
europepmc   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Inactivation of SERCA2 at Cys674 induces skeletal muscle atrophy by activating the TGFβ/Smad-S100a4 axis to promote inflammation. [PDF]

Redox Biol
Nan F, Liu S, Lei S, Peng Y, Zhang H, Chen X, Jin S, Mao Y, Lin D, Tong X, Qu Y.   +10 more
europepmc   +1 more source

Polyphenol dietary supplementation prevents inflammation‐induced muscle atrophy in a zebrafish (Danio rerio) model

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Diet‐induced inflammation is a major cause of muscle degeneration impacting human and animal health. Owing to their anti‐inflammatory and antioxidant properties, polyphenols have attracted considerable interest as feed additives.
Graziella Orso, Monica Matuozzo, Mariapina Rocco, Seyed Hossein Hoseinifar, Ghasem Ashouri, Andrea Scaloni, Marina Paolucci, Chiara D'Ambrosio, Roberta Imperatore   +8 more
wiley   +1 more source

Current Progress in the Role of Ferroptosis in Skeletal Muscle Atrophy. [PDF]

Mediators Inflamm
Chen Y, Guo Y, Zhao Z, Yang S, Guo B, Xu J.   +5 more
europepmc   +1 more source