Results 101 to 110 of about 12,047 (235)

Injury-Induced Microvesicle Particle Release in Human Skin Explant Tissue

open access: yes, 2017
Microvesicle particles (MVP) are 100-1000 nm vesicles that bud from the cell membrane and transmit intercellular signals locally and systemically via their bioactive cargo (e.g. cytokines).
Liu, Langni   +5 more
core  

Shared and specific molecular mechanisms of proteasome inhibitors in chemotherapy‐induced peripheral neurotoxicity

open access: yesBritish Journal of Pharmacology, EarlyView.
This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon   +27 more
wiley   +1 more source

Dermal and epidermal cell functions in the growth and regeneration of hair follicles and other skin appendages [PDF]

open access: yes, 1998
Epithelial-mesenchymal interactions are central to the development of skin and skin appendages in vertebrates. These interactions continue throughout adult life and underpin the cyclic growth and loss of hair in mammals. While the molecular basis of such
Gharzi, Ahmad
core  

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos   +3 more
wiley   +1 more source

Penetration enhancement effects of topically applied crosslinked hyaluronic acid

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Cross‐linked hyaluronic acid (HA) was demonstrated to enhance the topical delivery of a variety of hydrophilic actives into the skin. This phenomenon was observed for both small molecules and macromolecules, the latter of which was analysed with MALDI mass spectrometry imaging (MALDI‐MSI).
Aaron Cohen   +7 more
wiley   +1 more source

The effect of a serum containing acetyl hexapeptide‐8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies

open access: yesInternational Journal of Cosmetic Science, EarlyView.
The novel serum demonstrates significant anti‐skin aging effects, effectively improving static and dynamic wrinkles and skin texture. Therefore, this formulation holds promise as a safe and effective product in the field of anti‐wrinkle skincare products.
Mingjie Zhu   +14 more
wiley   +1 more source

CD4+ and CD8+ skin-associated T lymphocytes in canine atopic dermatitis produce interleukin-13, interleukin-22 and interferon-γ and contain a CD25+FoxP3+ subset

open access: yes, 2014
Background: T Cells play a major role in the immunopathogenesis of canine atopic dermatitis (cAD). However, the significance of cutaneous regulatory T cells (Tregs) and CD8+ T cells is currently unclear. Hypothesis/Objectives: The study aimed to evaluate
Rutten, Victor P M G   +4 more
core   +2 more sources

Unravelling polyphenol skin permeation: A comparative study using full‐thickness 3D in vitro and ex vivo human skin models

open access: yesInternational Journal of Cosmetic Science, EarlyView.
This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques   +6 more
wiley   +1 more source

Exploring Plant Stilbenes For Healthy Skin [PDF]

open access: yes, 2018
Accumulating evidence supports pharmacological roles for the plant stilbene, resveratrol in aging and disease contexts. Pterostilbene, a derivative of resveratrol, has been shown to have higher bioavailability and bio-efficacy than resveratrol, but is ...
Hawkins, Erica
core  

A Novel Method for the Isolation of Skin Resident T Cells from Normal and Diseased Human Skin

open access: yes, 2006
T cells resident in normal skin likely conduct immunosurveillance and are implicated in the development of inflammatory disorders such as psoriasis. This population of cells is difficult to study because existing techniques allow isolation of only few ...
Clark, Rachael A.   +6 more
core   +1 more source

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