Results 81 to 90 of about 12,047 (235)

UV-independent induction of beta defensin 3 in neonatal human skin explants [v2; ref status: indexed, http://f1000r.es/53b]

F1000Research, 2015
In order to determine the effect of UV radiation on β-defensin 3 (BD3) expression in human skin, freshly-isolated UV-naïve skin was obtained from newborn male infants undergoing planned circumcision.
Erin Wolf Horrell, John D'Orazio
doaj   +1 more source

Adaptive Pudendal Nerve Stimulation: A Pilot Study on Safety, Technical Feasibility, and Clinical Effect

Neurourology and Urodynamics, EarlyView.
ABSTRACT Purpose To evaluate the safety, procedural feasibility, and pilot clinical outcomes for a new implanted device delivering adaptive pudendal nerve stimulation. Materials and Methods Thirteen adult women with treatment‐refractory mixed (n = 8) or urge (n = 5) urinary incontinence were implanted with a Picostim‐DyNeuMo system incorporating an ...
Siemen Herroelen, Charles H. Knowles, Sean Doherty, Mo Benjaber, Jacob Kerr, Karen Wendt, Aidan Crawley, Tim Denison, Stefan De Wachter   +8 more
wiley   +1 more source

Apple scar skin viroid causes dapple and scar skin apple diseases by disrupting phenylpropanoid‐mediated metabolic pathways

New Plant Protection, EarlyView.
Dapple apple and scar skin apple diseases are closely associated with suppression of anthocyanin biosynthesis and enhancement of suberin biosynthesis. Apple scar skin viroid (ASSVd) infection represses anthocyanin biosynthesis in apple callus. Abstract Apple scar skin viroid (ASSVd) causes dapple and scar skin apple diseases, posing serious threats to ...
Lingzhu He, Huiyuan Xu, Tao Zhou, Naoi Takashi, Sano Teruo, Guojun Hu, Jipeng Xie, Xiuling Yang, Shifang Li, Zhixiang Zhang   +9 more
wiley   +1 more source

UV-independent induction of beta defensin 3 in neonatal human skin explants [v1; ref status: indexed, http://f1000r.es/4s2]

F1000Research, 2014
In order to determine the effect of UV radiation on β-defensin 3 (BD3) expression in human skin, freshly-isolated UV-naïve skin was obtained from newborn male infants undergoing planned circumcision.
Erin Wolf Horrell, John D'Orazio
doaj   +1 more source

HPV-DNA is not detectable in outgrowing cells from explant cultures of skin lesions established at the air-liquid-interface

, 2000
Keratinocyte cultures established from HPV containing skin cancers were described earlier to lose their HPV DNA after passaging in vitro. A different approach was therefore used in this study. Explant cultures were generated by depositing small pieces of
Mulder, Linda H.C., Boxman, Ingeborg L.A., Vermeer, Bert Jan, Ter Schegget, Jan, Bouwes Bavinck, Jan Nico, Schegget, Jan, Ter, Ponec, Maria   +6 more
core   +1 more source

Newly born mesenchymal cells exhibit rapid migration in embryonic chicken skin.

, 2023
(A) Single z-planes from confocal time-lapse series of an E6 Chameleon chicken skin explant culture treated with cell permeant TAT-Cre and cultured for 24 h. Magenta dots highlight mother and daughter cells.
Yuhang Chen (584479), Luigi Sedda (587440), Shahzeb Raja Noureen (17041575), Richard L. Mort (17041593), Connor A. Bain (17041581), James D. Glover (17041578), Michael L. Crichton (17041590), Arianna Berbeglia (17041584), Christian A. Yates (12462891), William K. W. Ho (6387527), Helen Brown (423601), Denis J. Headon (17041596), Jon Riddell (4240438), Calum Anderson (17041587)   +13 more
core   +1 more source

The Antiseptic Octenidine Inhibits Langerhans Cell Activation and Modulates Cytokine Expression upon Superficial Wounding with Tape Stripping

Journal of Immunology Research, 2019
Ideal agents for the topical treatment of skin wounds should have antimicrobial efficacy without negative influence on wound healing. Octenidine (OCT) has become a widely used antiseptic in professional wound care, but its influence on several components
Nenad Nikolić, Philip Kienzl, Pooja Tajpara, Martin Vierhapper, Johannes Matiasek, Adelheid Elbe-Bürger   +5 more
doaj   +1 more source

CLEC14A correlates with neutrophil infiltration in hepatocellular carcinoma and mediates neutrophil recruitment across liver endothelial cells

The Journal of Pathology, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke, Dean Kavanagh, Ayla O'Keeffe, Kylie Savoye, Kaiyi Yang, Daniel A Patten, Catherine E Willoughby, Josep M Llovet, Georgiana Neag, Helen L Reeves, Peter W Hewett, Neena Kalia, Tahir Shah, Yuk Ting Ma, Kelly Hunter, Joe Flint, Jack L McMurray, Owen Cain, Fabian Spill, Derek A Mann, Amy J Naylor, Victoria Heath, Christopher J Weston, Roy Bicknell, Shishir Shetty   +24 more
wiley   +1 more source

Interleukin-32 promotes detachment and activation of human Langerhans cells in a human skin explant model

, 2018
International audienceBACKGROUND: Cross-talk between skin keratinocytes (KCs) and Langerhans cells (LCs) plays a fundamental role in the body's first line of immunological defences.
O. Bonduelle, B. Combadière, Combadiere, B., M. Mimoun, Gonnet, J., Boccara, D., Mimoun, M., Atlan, M., J. Gonnet, A. Soria, H. Perrin, Bonduelle, O., A.J. Hutton, D. Boccara, M. Atlan, Perrin, H., Hutton, A.J., Atlan, Michael, Soria, A.   +18 more
core   +1 more source

Characterization of a pathogenic nonmigratory fibroblast population in systemic sclerosis skin

JCI Insight
Fibroblasts are central to pathogenesis of systemic sclerosis (SSc). However, studies of conventional explant fibroblast cultures incompletely reflect disease biology and treatment response.
Kristina E.N. Clark, Shiwen Xu, Moustafa Attar, Voon H. Ong, Christopher D. Buckley, Christopher P. Denton   +5 more
doaj   +1 more source