Results 81 to 90 of about 22,408 (233)

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

open access: yesAdvanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang   +10 more
wiley   +1 more source

Establishment of primary keratinocyte culture from horse tissue biopsates

open access: yesActa Agriculturae Slovenica, 2015
Primary cell lines established from skin tissue can be used in immunological, proteomic and genomic studies as in vitro skin models. The goal of our study was to establish a primary keratinocyte cell culture from tissue biopsates of two horses.
Jernej OGOREVC   +4 more
doaj   +1 more source

Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission

open access: yesThe Journal of Clinical Investigation, 2022
During cutaneous tick attachment, the feeding cavity becomes a site of transmission for tick salivary compounds and tick-borne pathogens. However, the immunological consequences of tick feeding for human skin remain unclear.
Johanna Strobl   +17 more
doaj   +1 more source

Epithelial Migration and Non-adhesive Periderm Are Required for Digit Separation during Mammalian Development. [PDF]

open access: yes, 2020
The fusion of digits or toes, syndactyly, can be part of complex syndromes, including van der Woude syndrome. A subset of van der Woude cases is caused by dominant-negative mutations in the epithelial transcription factor Grainyhead like-3 (GRHL3), and ...
Andersen, Bogi   +11 more
core   +2 more sources

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas   +6 more
wiley   +1 more source

Uncoupling TGFβ1 signalling from collagen protein synthesis in Dupuytren's disease. [PDF]

open access: yesJ Pathol
Abstract Dupuytren's disease is a fibroproliferative disorder of the palmer fascia (PF) characterised by flexion contractures in the hand. Dupuytren's disease can be treated surgically, but disease recurrence rates are high, potentially due to continual production of matrisomal proteins.
Cooper G   +12 more
europepmc   +2 more sources

Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation. [PDF]

open access: yes, 2018
Development of complex neural circuits like the peripheral somatosensory system requires intricate mechanisms to ensure axons make proper connections. While much is known about ligand-receptor pairs required for dorsal root ganglion (DRG) axon guidance ...
Estep, Jason A   +5 more
core   +2 more sources

Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang   +7 more
wiley   +1 more source

Role of carbon dioxide and ion transport in the formation of sub-embryonic fluid by the blastoderm of the Japanese quail [PDF]

open access: yes, 2002
1. The explanted blastoderm of the Japanese quail was used to explore the role of ions and carbon dioxide in determining the rate of sub-embryonic fluid (SEF) production between 54 and 72 h of incubation. 2.
AR A.   +27 more
core   +1 more source

Assessing the viability of genebanked seeds from rare, wild plants native to the United States using the D.E.A.D. paradigm

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Genebanks must maintain viable seeds for decades. Seeds that germinate are clearly alive, but some seeds, often from wild populations, do not germinate because they are dormant, empty, aged, or damaged (D.E.A.D.). This work evaluates the effects of D.E.A.D.
Christina Walters   +33 more
wiley   +1 more source

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