Results 41 to 50 of about 592,890 (313)

Basophils in skin inflammation

Japanese Journal of Clinical Immunology, 2011
Basophils represent less than 1% of peripheral blood leukocytes. Under physiological conditions, basophils principally circulate in peripheral blood, while mast cells reside in peripheral tissues. Like mast cells, they express the high-affinity IgE receptor on their cell surface and release chemical mediators.
openaire   +3 more sources

Thalidomide Attenuates Skin Lesions and Inflammation in Rosacea-Like Mice Induced by Long-Term Exposure of LL-37 [PDF]

, 2022
Yumeng Kang,1 Chuanxi Zhang,1 Yang He,1 Ziyan Zhang,1 Heliang Liu,2 Zhongqiu Wei,3 Jie Yang1 1Department of Dermatology, Affiliated Hospital of North China University of Science and Technology, Tangshan, People’s Republic of China; 2Hebei Key Laboratory ...
Liu H, Yang J, He Y, Zhang Z, Zhang C, Wei Z, Kang Y   +6 more
core  

Impact of Age and Body Site on Adult Female Skin Surface pH [PDF]

, 2012
Background: pH is known as an important parameter in epidermal barrier function and homeostasis. Aim: The impact of age and body site on skin surface pH (pH(SS)) of women was evaluated in vivo.
Korting, Hans Christian, Meier, Robert Johannes, Landthaler, Michael, Schreml, Stephan, Zeller, Veronika, Babilas, Philipp, Korting, H. C., Behm, Barbara   +7 more
core   +1 more source

Morbidity and Causes of Death in Patients with Cutaneous T-cell Lymphoma in Finland

Acta Dermato-Venereologica, 2017
Cutaneous T-cell lymphomas (CTCL), especially mycosis fungoides, can be considered as a state of longstanding low-grade systemic inflammation.
Liisa Väkevä, Tuomas Lipsanen, Harri Sintonen, Annamari Ranki   +3 more
doaj   +1 more source

Neutrophils Affect IL-33 Processing in Response to the Respiratory Allergen Alternaria alternata

Frontiers in Immunology, 2021
Future precision medicine requires further clarifying the mechanisms of inflammation in the severe endotypes of chronic airway diseases such as asthma and chronic rhinosinusitis (CRS).
Sharon Van Nevel, Judith van Ovost, Gabriele Holtappels, Natalie De Ruyck, Nan Zhang, Harald Braun, Harald Braun, Tania Maes, Claus Bachert, Claus Bachert, Olga Krysko   +10 more
doaj   +1 more source

Skin-targeted inhibition of PPAR β/δ by selective antagonists to treat PPAR β/δ-mediated psoriasis-like skin disease in vivo [PDF]

, 2012
We have previously shown that peroxisome proliferator activating receptor ß/d (PPAR ß/d is overexpressed in psoriasis. PPAR ß/d is not present in adult epidermis of mice.
Kevin D. Read (165019), Palmer Colin, Kally Booth, Katrin Hack, Booth Kally, Colin Palmer (165015), Suzanne Norval, Read, Kevin D, Hack Katrin, John Foerster (165047), Robert Kime, Kevin D Read, John Foerster, Kally Booth (165039), Louise Reilly, Suzanne Norval (165024), Read Kevin D., Palmer, Colin; id_orcid, Norval, Suzanne, Reilly, Louise, Louise Reilly (165006), Reilly Louise, Read, Kevin, Palmer, Colin, Hack, Katrin, Robert Kime (165030), Colin Palmer, Kime Robert, Foerster John, Foerster, John, Katrin Hack (165002), Kime, Robert, Norval Suzanne, Booth, Kally   +33 more
core   +1 more source

IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE

Nature Communications, 2018
Systemic lupus erythematosus (SLE) is associated with altered B cell responses but the underlying aetiology is still unclear. Here the authors show that a CD11chiT-bet+ B cell subset with a unique phenotype and transcriptome is increased in patients with
Shu Wang, Jingya Wang, Varsha Kumar, Jodi L. Karnell, Brian Naiman, Phillip S. Gross, Saifur Rahman, Kamelia Zerrouki, Richard Hanna, Christopher Morehouse, Nicholas Holoweckyj, Hao Liu, Autoimmunity Molecular Medicine Team, Zerai Manna, Raphaela Goldbach-Mansky, Sarfaraz Hasni, Richard Siegel, Miguel Sanjuan, Katie Streicher, Michael P. Cancro, Roland Kolbeck, Rachel Ettinger   +21 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Genome Wide Transcriptome Analysis of Dendritic Cells Identifies Genes with Altered Expression in Psoriasis [PDF]

, 2013
Activation of dendritic cells by different pathogens induces the secretion of proinflammatory mediators resulting in local inflammation. Importantly, innate immunity must be properly controlled, as its continuous activation leads to the development of ...
Szász, András, István Nagy (147904), Vilmos Tubak (455817), Kemény Lajos, Kondorosi, Éva, András Szász, Zoltán Hegedűs (455815), Tubak Vilmos, Lajos Kemény, Éva Kondorosi (3507242), Kata Filkor (455814), Kondorosi Éva, Nagy István, Tubák, Vilmos, Lajos Kemény (229288), Hegedűs Zoltán, Szász András, István Nagy, Kemény, Lajos, Éva Kondorosi, Nagy, István, Filkor, Katalin, Vilmos Tubak, Filkor Kata, Hegedűs, Zoltán, András Szász (455816), Kata Filkor, Zoltán Hegedűs   +27 more
core   +1 more source

Chronic Comorbidities Contribute to the Burden and Costs of Persistent Asthma

Mediators of Inflammation, 2015
Background. We aimed to study the prevalence of chronic comorbidities in asthma patients and the costs of health care use associated with asthma with comorbidities. Material and Methods. We analysed the prevalence of the four most common chronic diseases
Paula Kauppi, Miika Linna, Juha Jantunen, Jaana E. Martikainen, Tari Haahtela, Anna Pelkonen, Mika Mäkelä   +6 more
doaj   +1 more source