Results 51 to 60 of about 592,890 (313)

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source

Epidermal Junctions and Skin Inflammation

Journal of Clinical Medicine, 2022
Epidermal junctions help to preserve cutaneous homeostasis and, consequently, protect the body against a wide range of environmental stresses [...]
openaire   +3 more sources

Alpha-1 adrenoceptor stimulation triggers axon-reflex vasodilatation in human skin [PDF]

, 2009
The aim of this study was to determine whether pre-treatment of human skin with the α1-adrenoceptor antagonist terazosin would block vasoconstrictor responses and axon-reflex vasodilatation to the α1-adrenoceptor agonist methoxamine.
Drummond, P.D.
core   +1 more source

Skin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cells. [PDF]

, 2012
The TLR7 agonist imiquimod has been used successfully as adjuvant for skin treatment of virus-associated warts and basal cell carcinoma. The effects of skin TLR7 triggering on respiratory leukocyte populations are unknown.
Lohmeyer, Jürgen, Werner von Wulffen (141047), Gruber, Achim D., Gregor Bein (141053), Knoche, Angela, Kershaw, Olivia, Kranz, Sabine, Angela Knoche (141037), Holger Hackstein (141030), Hagel, Nicole, Angela Knoche, Wulffen, Werner von, Olivia Kershaw (141049), Holger Hackstein, Olivia Kershaw, Achim D. Gruber (141051), Nicole Hagel, Gregor Bein, Jürgen Lohmeyer, Sabine Kranz, Nicole Hagel (141033), Baal, Nelli, Bein, Gregor, Achim D Gruber, Jürgen Lohmeyer (141044), Nelli Baal (141055), Hackstein, Holger, Nelli Baal, Werner von Wulffen, Sabine Kranz (141040)   +29 more
core   +1 more source

The G Protein-Coupled Receptor (GPR) 15 Counteracts Antibody-Mediated Skin Inflammation

Frontiers in Immunology, 2020
The G protein-coupled receptor 15 (GPR15) has recently been highlighted as an important regulator of T cell trafficking into the gut under physiological and pathophysiological conditions.
Lina Jegodzinski, Tanya Sezin, Karin Loser, Sadegh Mousavi, Detlef Zillikens, Detlef Zillikens, Christian D. Sadik, Christian D. Sadik   +7 more
doaj   +1 more source

In Vitro and Ex Vivo Models for Screening Topical Anti-Inflammatory Drugs

Scientia Pharmaceutica, 2023
Skin inflammation occurs as an immune response to various stimuli such as ultraviolet light, irritants, or any type of skin barrier injury. Finding safe and effective drugs to combat skin inflammation remains a research challenge.
Juan Luis Pérez-Salas, Martha Rocío Moreno-Jiménez, Nuria Elizabeth Rocha-Guzmán, Rubén Francisco González-Laredo, Luis Medina-Torres, José Alberto Gallegos-Infante   +5 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Fibroblast Growth Factor 22 is not essential for skin development and repair but plays a role in tumorigenesis [PDF]

, 2012
Fibroblast Growth Factors play critical roles during development, tissue homeostasis and repair by controlling cell proliferation, survival, migration and differentiation.
Robbez-Masson, L, Ian Rosewell, Grose Richard, Cross, B, Rosewell, I, Athina-Myrto Chioni (156542), Robbez-Masson, Luisa, Rosewell Ian, Chioni Athina-Myrto, Jarosz, Monika, Barbara Cross (156544), Barbara Cross, Grose, Richard, Chioni, A-M, Rosewell, Ian, Cross Barbara, Richard Grose (156552), Chioni, Athina-Myrto, Cross, Barbara, Jarosz, M, Luisa Robbez-Masson (156539), Grose, R, Luisa Robbez-Masson, Jarosz Monika, Ian Rosewell (156548), Monika Jarosz, Richard Grose, Robbez-Masson Luisa, Monika Jarosz (156537), Athina-Myrto Chioni   +29 more
core   +1 more source

Comorbidities of chronic rhinosinusitis in children and adults

Clinical and Translational Allergy
Background Chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the nose and paranasal sinuses lasting ≥12 weeks. CRS may exist with (CRSwNP) or without (CRSsNP) nasal polyps.
Aada Murtomäki, Alma Helevä, Paulus Torkki, Jari Haukka, Anna Julkunen‐Iivari, Riikka Lemmetyinen, Mika Mäkelä, Aarno Dietz, Mikko Nuutinen, Sanna Toppila‐Salmi   +9 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source