Results 41 to 50 of about 911,787 (405)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

TORQUE RIPPLE RATE REDUCTION OF 6/4 SWITCHED RELUCTANCE MOTOR USING SLIDING MODE LEARNING CONTROLS

Mağallaẗ Al-kūfaẗ Al-handasiyyaẗ
This paper presents a sliding mode control for reducing the torque ripple of a 6/4 switched reluctance motor. Several types of sliding mode control based on the current variable are implemented: conventional sliding mode control, learning sliding mode ...
Zahraa Razaq Mohammed, Abdal-Razak Shehab Hadi   +1 more
doaj   +1 more source

Sliding mode based piezoelectric actuator control [PDF]

, 2004
In this paper a control of method for a piezoelectric stack actuator control is proposed. In addition briefly the usage of the same methods for estimation of external force acting to the actuator in contact with environment is discussed.
Abidi, Khalid Seyed, Sabanovic, Asif, Şabanoviç, Asif   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Sliding Mode Control for Trajectory Tracking of a Non-holonomic Mobile Robot using Adaptive Neural Networks [PDF]

, 2014
In this work a sliding mode control method for a non-holonomic mobile robot using an adaptive neural network is proposed. Due to this property and restricted mobility, the trajectory tracking of this system has been one of the research topics for the ...
Carelli Albarracin, Ricardo Oscar, Rossomando, Francisco Guido, Soria, Carlos Miguel   +2 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Teaching, Analyzing, Designing and Interactively Simulating of Sliding Mode Control [PDF]

, 2018
This paper introduces an interactive methodology to analize, design, and simulate sliding model controllers for R2 linear systems. This paper reviews sliding mode basic concepts and design methodologies and describes an interactive tool which has been ...
Carrero Candelas, Niliana Andreina, Costa Castelló, Ramon, Dormido Bencomo, Sebastián, Fossas Colet, Enric   +3 more
core   +3 more sources

Robust position control of ultrasonic motor using VSS observer [PDF]

, 2010
Intrinsic properties of ultrasonic motor (high torque for low speed, high static torque, compact in size, etc.) offer great advantages for industrial applications. However, when load torque is applied, dead-zone occurs in control input.
Darba, Araz, Odomari, Shogo, Senjyu, Tomonobu, Uchida, Kosuke, Yona, Atsushi   +4 more
core   +1 more source

Sliding Mode Based Behavior Control

, 2004
{"references": ["R. C. Arkin, Behavior-based robotics. Cambridge, Mass.: MIT Press,\n1998.", "J. Ferber, Multi-agent systems: an introduction to distributed artificial\nintelligence. Harlow, Eng.: Addison-Wesley, 1999.", "W. L. Xu and S. K. Tso, \"Sensor-Based Fuzzy Reactive Navigation of a\nMobile Robot Through Local Target Switching,\" IEEE Trans. on\
Yannier, Selim, Şabanoviç, Asif, Onat, Ahmet, Baştan, Muhammet   +3 more
openaire   +2 more sources