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Structural and functional insights of the podocyte slit diaphragm complex

Tissue Barriers
Glomerular podocytes, specialized epithelial cells, are central to the filtration function of vertebrate kidneys. Through their interdigitating foot processes, podocytes provide epithelial coverage to capillaries. They maintain selective filtration by allowing water, ions, and small solutes to filter while retaining proteins and larger molecules in the
Abrar H. Qadri   +4 more
openaire   +2 more sources

β-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity

Proceedings of the National Academy of Sciences of the United States of America, 2006
Ivo Quack, Peter Gerke, Oliver Vonend
exaly  

CIN85/RukL Is a Novel Binding Partner of Nephrin and Podocin and Mediates Slit Diaphragm Turnover in Podocytes

Journal of Biological Chemistry, 2010
Beina Teng   +2 more
exaly  

The podocyte slit diaphragm—from a thin grey line to a complex signalling hub

Nature Reviews Nephrology, 2013
Florian Grahammer   +2 more
exaly  

SIRPα interacts with nephrin at the podocyte slit diaphragm

FEBS Journal, 2012
Yuko Kajiho   +2 more
exaly  

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