Results 191 to 200 of about 17,762 (221)

Piezo, Nephrocyte Function, and Slit Diaphragm Maintenance in Drosophila

Journal of the American Society of Nephrology
Key Points Piezo channels, known for detecting mechanical pressure, were found to be expressed at the lacuna channel membranes of nephrocytes.Piezo loss of function caused nephrocyte dysfunction, including disrupted slit diaphragm structure and altered lacuna channel morphology.Piezo deficiency
Yunpo Zhao, Jianli Duan, Iden D. Han, Joyce van de Leemput, Patricio E. Ray, Zhe Han   +5 more
openaire   +2 more sources

The slit diaphragm: a signaling platform to regulate podocyte function

Current Opinion in Nephrology and Hypertension, 2005
The discovery of nephrin and other slit diaphragm proteins dramatically expanded our knowledge of the molecular make-up of the glomerular filter of the kidney. This review focuses on the most recent evidence elucidating the dynamic functions of the slit diaphragm and stresses the importance of slit diaphragm proteins in mediating signal transduction in
Huber, Tobias B., Benzing, Thomas
openaire   +3 more sources

SIRPα interacts with nephrin at the podocyte slit diaphragm

The FEBS Journal, 2012
The slit diaphragm (SD) is an intercellular junction between renal glomerular epithelial cells (podocytes) that is essential for permselectivity in glomerular ultrafiltration. The SD components, nephrin and Neph1, assemble a signaling complex in a tyrosine phosphorylation dependent manner, and regulate the unique actin cytoskeleton of podocytes ...
Yuko, Kajiho, Yutaka, Harita, Hidetake, Kurihara, Shigeru, Horita, Atsuko, Matsunaga, Haruko, Tsurumi, Shoichiro, Kanda, Noriko, Sugawara, Kenichiro, Miura, Takashi, Sekine, Seisuke, Hattori, Motoshi, Hattori, Takashi, Igarashi   +12 more
openaire   +2 more sources

Role of podocyte slit diaphragm as a filtration barrier.

Nephrology (Carlton, Vic.), 2007
Although the role of glomerular basement membrane has been emphasised as the barrier for retaining plasma proteins in the past three decades, some recent studies have demonstrated that the slit diaphragm of the glomerular epithelial cell (podocyte) is the structure likely to be the barrier in the glomerular capillary wall.
Hiroshi, Kawachi, Naoko, Miyauchi, Koichi, Suzuki, Gi Dong, Han, Michiaki, Orikasa, Fujio, Shimizu   +5 more
openaire   +2 more sources

Slit Diaphragms: Junctions That Never Sleep

Journal of the American Society of Nephrology, 2022
openaire   +2 more sources

In vivo slit diaphragm dynamics in Drosophila

Nature Reviews Nephrology, 2022
openaire   +2 more sources

Confinement-Controlled Aqueous Chemistry within Nanometric Slit Pores

Chemical Reviews, 2021
Daniel Muñoz-Santiburcio
exaly  

Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis

Nature, 2020
Bernardo Tavora, Tobias Mederer, Simon Ruffing   +2 more
exaly  

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

Nature Genetics, 2005
Mehmet M Altintas, Christian Faul, Raghu Kalluri   +2 more
exaly  

Double-slit photoelectron interference in strong-field ionization of the neon dimer

Nature Communications, 2019
Maksim Kunitski, Florian Trinter, Anton Kalinin   +2 more
exaly