Results 221 to 230 of about 165,371 (351)

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Electro-acupuncture attenuates cyclophosphamide-induced premature ovarian insufficiency in rats through miRNA regulation and TGFβ/Smad pathway modulation. [PDF]

Am J Transl Res
Xian J, Zhao R, Chen Y, Khan MJ, Jamil M, Alfuraydi AA, Alsabih AO, Almutairi S, Umair M, Hameed Y.   +9 more
europepmc   +1 more source

Intrauterine infusion of platelet‐rich plasma improves fibrosis by transforming growth factor beta 1/Smad pathway in a rat intrauterine adhesion model

Hongwen Yang, Wenmin Zhang, Jingchuan Fang, Zhi‐Han Tang, Yanni Zhou, Hongzhen Hu, Miao Miao, Yu Yao   +7 more
openalex   +1 more source

Correction to: NKX2-1 Activation by SMADS Signaling After Definitive Endoderm Differentiation in Human Embryonic Stem Cell by Li YU, Eggermont K, Vanslembrouch V, and Verfaillie CM. Stem Cells Dev 2013;22;9:1433–1442 DOI:10.1089/scd.2012.0620

, 2020

openalex   +2 more sources

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Amhy/Amhr2y-mediated sex determination in two distantly related teleosts relies on the conserved Alk3-Smad5 axis. [PDF]

Mol Biol Evol
Zhou L, Zhang L, Qu Z, Jian H, Zheng S, Li M, Wang D, Liu X.   +7 more
europepmc   +1 more source

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells [PDF]

, 2018
Peng Wang, Esra Karaköse, Hongtao Liu, Ethan Swartz, Courtney Ackeifi, Viktor Zlatanic, Jessica Wilson, Bryan J. González, Aaron Bender, Karen K. Takane, Lillian Ye, George Harb, Felicia W. Pagliuca, Dirk Homann, Dieter Egli, Carmen Argmann, Donald K. Scott, Adolfo Garcı́a-Ocaña, Andrew F. Stewart   +18 more
openalex   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

The effect and safety of small-molecule antiviral drugs on long prognosis of post-COVID-19 pulmonary fibrosis: a real-world study in China. [PDF]

Front Microbiol
Xu Y, Lu M, Li Y, Den X, Peng D, Zhou F, Li A, Hou T, Xiang T.   +8 more
europepmc   +1 more source

Supplementary Tables from Transcriptional Induction of Periostin by a Sulfatase 2–TGFβ1–SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma

, 2023
Gang Chen, Ikuo Nakamura, Renumathy Dhanasekaran, Eriko Iguchi, Ezequiel J. Tolosa, Paola Romecín, Renzo E. Vera, Luciana L. Almada, Alexander G. Miamen, Roongruedee Chaiteerakij, Mengtao Zhou, Michael K. Asiedu, Catherine D. Moser, Shaoshan Han, Chunling Hu, Bubu A. Banini, Abdul M. Oseini, Yi‐Chun Chen, Yong Fang, Dongye Yang, Hassan M. Shaleh, Shaoqing Wang, Dehai Wu, Tao Song, Ju‐Seog Lee, Snorri S. Thorgeirsson, Éric Chevet, Vijay H. Shah, Martín E. Fernández-Zapico, Lewis R. Roberts   +29 more
openalex   +1 more source