Microbiota-gut-muscle axis shapes fish muscle texture by regulating collagen synthesis. [PDF]
Wang Z +7 more
europepmc +1 more source
Naringenin produces comprehensive renoprotective effects in rodent models of diabetic nephropathy. It mainly lowers blood sugar and alleviates renal dysfunction by reducing proteinuria, serum creatinine, and blood urea nitrogen. Meanwhile, naringenin improves antioxidant status by elevating glutathione and reducing malondialdehyde, and suppresses ...
Yuzhu Qu +7 more
wiley +1 more source
Anti-endoglin monoclonal antibody TRC105 prevents the increase of liver inflammatory biomarkers in a mouse model of cholestasis. [PDF]
Eissazadeh S +10 more
europepmc +1 more source
Miyamoto and colleagues found that introducer‐assisted multipass transpapillary biopsy could yield specimens suitable for comprehensive genomic profiling in biliary tract cancer, although suitability remained limited and panel dependent. Fresh frozen samples yielded markedly higher DNA quality than formalin‐fixed paraffin‐embedded samples, supporting ...
Kazuya Miyamoto +9 more
wiley +1 more source
A Novel Anti-Fibrotic Role of G-Protein-Coupled Receptor 119 in Hepatic Stellate Cells. [PDF]
Park J +6 more
europepmc +1 more source
ABSTRACT Background Benign tracheal stenosis, characterized by granulation hyperplasia, is a rare and serious disease threatening human health. Interventional bronchoscopy demonstrates limited therapeutic efficacy and poses a risk of re‐injury to the airway.
Dengyuan Li +4 more
wiley +1 more source
Disrupting the TGF-β-regulated epithelial-mesenchymal transition, apoptotic and autophagic phenotypes of 3D glioblastoma spheroids via glycolytic inhibition. [PDF]
Payet-Desruisseaux M +4 more
europepmc +1 more source
Tumor Plasticity and Microenvironmental Crosstalk as Drivers of Metastasis and Therapy Resistance
The graphical abstract is a schematic illustration of the bidirectional crosstalk between tumor plasticity and the tumor microenvironment (TME) in driving metastasis and therapy resistance. Tumor‐intrinsic factors such as genetic mutations and epigenetic reprogramming enable dynamic transitions between epithelial, mesenchymal, and cancer stem cell ...
Gunjan Dagar +12 more
wiley +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
Erratum: IGF2BP2-modified UBE2D1 Interacts with Smad2/3 to Promote the Progression of Breast Cancer. [PDF]
Guan XQ +13 more
europepmc +1 more source

