Results 201 to 210 of about 5,853,742 (252)

Cell penetrating peptide-functionalized small interfering RNA nanoparticles knock down HER expression in breast cancer cells. [PDF]

J Pharmacol Exp Ther
Dissanayake R, Mishra VK, Ahmed M.
europepmc   +1 more source

Sub‐1 ms Optoelectronic Synapse Based on {ZnCdO/ZnO} Multilayer Structure for High‐Speed Neuromorphic Vision Systems

Advanced Functional Materials, EarlyView.
Eu‐doped {ZnCdO/ZnO} structures grown on Si are developed, showcasing dual‐functionality controlled by europium doping. While high europium concentration transforms the device into an ultrafast, self‐powered photodetector, low‐doped structures can be used as an optoelectronic synapse.
Igor Perlikowski, Eunika Zielony, Adrian Kaim, Ewa Przeździecka   +3 more
wiley   +1 more source

Cholesterol-dependent control of endosomal escape regulates intracellular trafficking of small interfering RNA therapeutics and interactions with small molecule drugs. [PDF]

J Pharmacol Exp Ther
Tawfik SM, Giang Nguyen LT, Jin J, Armanios B, Zhong XB.   +4 more
europepmc   +1 more source

Sacrificial‐Layer‐Assisted Heat‐Affected‐Zone Suppression in Laser Patterning of PET for High‐Performance Flexible Devices

Advanced Functional Materials, EarlyView.
A removable sacrificial polymer layer engineers the thermal boundary condition during nanosecond laser ablation of PET, suppressing heat‐affected‐zone formation without relying on costly ultrafast lasers. This strategy enables deep, high‐aspect‐ratio trenches with no detectable heat‐affected zone, templating silver‐filled mesh electrodes with record ...
Mehdi Zarei, Mirza Sahaluddin, Mostafa Bedewy, Paul W. Leu   +3 more
wiley   +1 more source

In Silico Development of a Targeted Small Interfering RNA (siRNA) Sequence to Silence Goblet Cell Mucin-5AC Overexpression in Cystic Fibrosis. [PDF]

Cureus
Ahluwalia J, Katakam A, Revuri N, Satish S.   +3 more
europepmc   +1 more source

Nitride MXenes Beyond Carbides: Bridging the Gap Between Computational Prediction and Experimental Realization

Advanced Functional Materials, EarlyView.
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley   +1 more source

Preclinical safety and bleeding evaluation in swine for a small interfering RNA-lipid nanoparticle that prevents excess fibrinogen synthesis. [PDF]

J Thromb Haemost
Seadler MS, Ferraresso F, Turner HM, Ketelboeter LM, Zhang Y, Badior K, Hayssen WG, Chen T, Haugen AL, Cau MF, Robertson M, Skaer C, Bansal M, Murphy PB, de Moya M, Dyer MR, Kastrup CJ.   +16 more
europepmc   +1 more source

Out‐of‐Plane Strain‐Decoupled Architecture for High‐Fill‐Factor Stretchable OLED Displays

Advanced Functional Materials, EarlyView.
A vertically decoupled multilayer SOLED architecture separates emissive pixel islands from deformable interconnects, allowing low‐modulus elastomeric layers to accommodate applied strain and suppress strain transfer to the OLED region. This design, combined with transparent hybrid encapsulation, enables a high fill factor (∼75%), stretchability ...
Young Hyun Son, Kyung Cheol Choi, Jeong Hyun Kwon   +2 more
wiley   +1 more source

Small Interfering RNA (siRNA) in Dyslipidemia: A Systematic Review on Safety and Efficacy of siRNA. [PDF]

J Exp Pharmacol
Alla SSM, Shah DJ, Meyur S, Agarwal P, Alla D, Moraboina SL, Ghadvaje GV, Bayeh RG, Malireddi A, Shajan T, Vineetha B, Sai Prudhvi T, Biziyaremye P.   +12 more
europepmc   +1 more source

Unique Role of Microstructure of a Bioimplant Zinc Alloy and Protein Content of Simulated Body Fluid in Corrosion and Fracture

Advanced Functional Materials, EarlyView.
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman, Syed Hussain Wajahat, Saad Al‐Saadi, Robin E. Schäublin, Peng Zeng, Solomon Ansah, Jixing Lin, Xian Tong, Cuie Wen, Jörg F. Löffler   +9 more
wiley   +1 more source