Results 1 to 10 of about 5,655,190 (291)

Phased secondary small interfering RNAs in Panaxnotoginseng [PDF]

open access: yesBMC Genomics, 2018
Background Recent results demonstrated that either non-coding or coding genes generate phased secondary small interfering RNAs (phasiRNAs) guided by specific miRNAs. Till now, there is no studies for phasiRNAs in Panax notoginseng (Burk.) F.H.
Kun Chen   +11 more
doaj   +5 more sources

Small Interfering RNAs in the Management of Human Osteoporosis [PDF]

open access: yesBritish Medical Bulletin, 2023
Abstract Background Osteoporosis results in reduced bone mass and consequent bone fragility. Small interfering RNAs (siRNAs) can be used for therapeutic purposes, as molecular targets or as useful markers to test new therapies. Sources of data
Francesco Oliva
exaly   +5 more sources

Inhibition of Venezuelan Equine Encephalitis Virus Using Small Interfering RNAs [PDF]

open access: yesViruses, 2022
Acutely infectious new world alphaviruses such as Venezuelan Equine Encephalitis Virus (VEEV) pose important challenges to the human population due to a lack of effective therapeutic intervention strategies.
Amrita Haikerwal   +7 more
doaj   +2 more sources

Electroporation of Small Interfering RNAs into Tibialis Anterior Muscles of Mice [PDF]

open access: yesBio-Protocol, 2022
Aging and wasting of skeletal muscle reduce organismal fitness. Regrettably, only limited interventions are currently available to address this unmet medical need. Many methods have been developed to study this condition, including the intramuscular
Anna Stephan   +3 more
doaj   +2 more sources

Machine learning for small interfering RNAs: a concise review of recent developments [PDF]

open access: yesFrontiers in Genetics, 2023
The advent of machine learning and its subsequent integration into small interfering RNA (siRNA) research heralds a new epoch in the field of RNA interference (RNAi).
Minhyeok Lee
doaj   +2 more sources

Determining the defining lengths between mature microRNAs/small interfering RNAs and tinyRNAs [PDF]

open access: yesScientific Reports, 2023
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are loaded into Argonaute (AGO) proteins, forming RNA-induced silencing complexes (RISCs). The assembly process establishes the seed, central, 3′ supplementary, and tail regions across the loaded ...
GeunYoung Sim   +7 more
doaj   +2 more sources

Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach [PDF]

open access: yesInternational Journal of Nanomedicine, 2019
Ghanbar Mahmoodi Chalbatani,1,* Hassan Dana,1,2,* Elahe Gharagouzloo,1 Santiago Grijalvo,3,4 Ramon Eritja,3,4 Craig D Logsdon,5,6 Fereidoon Memari,1 Seyed Rouhollah Miri,1 Mahdi Rezvani Rad,7 Vahid Marmari21Cancer Research Center, Cancer Institute of ...
Mahmoodi Chalbatani G   +9 more
doaj   +2 more sources

Potential of siRNA in COVID-19 therapy: Emphasis on in silico design and nanoparticles based delivery

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Small interfering RNA (siRNA)-mediated mRNA degradation approach have imparted its eminence against several difficult-to-treat genetic disorders and other allied diseases.
Rushikesh Fopase   +6 more
doaj   +1 more source

smalldisco, a pipeline for siRNA discovery and 3′ tail identification

open access: yesG3: Genes, Genomes, Genetics, 2023
Capturing and sequencing small RNAs is standard practice; however, identification of a group of these small RNAs—small interfering RNAs (siRNAs)—has been more difficult.
Ian V Caldas   +3 more
doaj   +1 more source

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