Results 11 to 20 of about 125,699 (320)

Smallpox, Monkeypox and Other Human Orthopoxvirus Infections

open access: yesViruses, 2022
Considering that vaccination against smallpox with live vaccinia virus led to serious adverse effects in some cases, the WHO, after declaration of the global eradication of smallpox in 1980, strongly recommended to discontinue the vaccination in all ...
Galina A. Shchelkunova   +1 more
doaj   +2 more sources

Repositioning potentials of smallpox vaccines and antiviral agents in monkeypox outbreak: A rapid review on comparative benefits and risks

open access: yesHealth Science Reports, 2022
Background and aims There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on ...
Md. Rabiul Islam   +6 more
doaj   +2 more sources

Influence of Population Immunosuppression and Past Vaccination on Smallpox Reemergence

open access: yesEmerging Infectious Diseases, 2018
We built a SEIR (susceptible, exposed, infected, recovered) model of smallpox transmission for New York, New York, USA, and Sydney, New South Wales, Australia, that accounted for age-specific population immunosuppression and residual vaccine immunity and
C. Raina MacIntyre   +7 more
doaj   +2 more sources

Smallpox in the Post-Eradication Era

open access: yesViruses, 2020
Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world.
Hermann Meyer   +2 more
doaj   +2 more sources

The Role of Brincidofovir in Preparation for a Potential Smallpox Outbreak

open access: yesViruses, 2017
Smallpox (variola) virus is considered a Category A bioterrorism agent due to its ability to spread rapidly and the high morbidity and mortality rates associated with infection. Current recommendations recognize the importance of oral antivirals and call
Scott A. Foster   +2 more
doaj   +2 more sources

Are We Prepared in Case of a Possible Smallpox-Like Disease Emergence?

open access: yesViruses, 2017
Smallpox was the first human disease to be eradicated, through a concerted vaccination campaign led by the World Health Organization. Since its eradication, routine vaccination against smallpox has ceased, leaving the world population susceptible to ...
Victoria A. Olson, Sergei N. Shchelkunov
doaj   +2 more sources

Use of JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) for Preexposure Vaccination of Persons at Risk for Occupational Exposure to Orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022

open access: yesMMWR. Morbidity and mortality weekly report, 2022
Certain laboratorians and health care personnel can be exposed to orthopoxviruses through occupational activities. Because orthopoxvirus infections resulting from occupational exposures can be serious, the Advisory Committee on Immunization Practices ...
A. Rao   +10 more
semanticscholar   +1 more source

Duration of humoral immunity from smallpox vaccination and its cross-reaction with Mpox virus

open access: yesSignal Transduction and Targeted Therapy, 2023
The ongoing pandemic caused by mpox virus (MPXV) has become an international public health emergency that poses a significant threat to global health. The vaccinia virus Tiantan strain (VTT) was used to vaccinate against smallpox in China 42 years ago ...
Entao Li   +8 more
semanticscholar   +1 more source

Monkeypox virus-infected individuals mount comparable humoral immune responses as Smallpox-vaccinated individuals

open access: yesNature Communications, 2023
In early 2022, a cluster of monkeypox virus (MPXV) infection (mpox) cases were identified within the UK with no prior travel history to MPXV-endemic regions.
A. Otter   +26 more
semanticscholar   +1 more source

Effect of prior immunisation with smallpox vaccine for protection against human Mpox: A systematic review

open access: yesReviews in Medical Virology, 2023
Monkeypox is an emerging threat to humans since a new outbreak in May 2022. It is hypothesised that increasing the immunologically naive population after the cessation of the smallpox vaccination campaign in the 1980s is one of the leading causes of it ...
Fahima Akter   +7 more
semanticscholar   +1 more source

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