Results 11 to 20 of about 112,669 (274)

What Was the Primary Mode of Smallpox Transmission? Implications for Biodefense [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
The mode of infection transmission has profound implications for effective containment by public health interventions. The mode of smallpox transmission was never conclusively established.
Donald eMilton   +2 more
doaj   +3 more sources

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics. [PDF]

open access: yesMedComm (2020)
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yan Y   +14 more
europepmc   +2 more sources

History of Smallpox

open access: yesJournal of Nepal Medical Association, 2003
NA
P N Shrestha
doaj   +1 more source

Remaining Questions about Clinical Variola Major

open access: yesEmerging Infectious Diseases, 2011
After the recent summary of World Health Organization–authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the ...
J. Michael Lane
doaj   +1 more source

The origins and genomic diversity of American Civil War Era smallpox vaccine strains

open access: yesGenome Biology, 2020
Vaccination has transformed public health, most notably including the eradication of smallpox. Despite its profound historical importance, little is known of the origins and diversity of the viruses used in smallpox vaccination.
Ana T. Duggan   +21 more
doaj   +1 more source

Smallpox, Monkeypox and Other Human Orthopoxvirus Infections

open access: yesViruses, 2022
Considering that vaccination against smallpox with live vaccinia virus led to serious adverse effects in some cases, the WHO, after declaration of the global eradication of smallpox in 1980, strongly recommended to discontinue the vaccination in all ...
Galina A. Shchelkunova   +1 more
doaj   +1 more source

Urban inoculation and the decline of smallpox mortality in eighteenth-century cities-a reply to Razzell. [PDF]

open access: yes, 2015
Smallpox was probably the single most lethal disease in eighteenth-century Britain but was reduced to a minor cause of death by the mid-nineteenth century due to vaccination programmes post-1798.
Boulton, Jeremy   +2 more
core   +2 more sources

Progression of pathogenic events in cynomolgus macaques infected with variola virus. [PDF]

open access: yesPLoS ONE, 2011
Smallpox, caused by variola virus (VARV), is a devastating human disease that affected millions worldwide until the virus was eradicated in the 1970 s.
Victoria Wahl-Jensen   +10 more
doaj   +1 more source

Struggling to a monumental triumph : Re-assessing the final stages of the smallpox eradication program in India, 1960-1980 [PDF]

open access: yes, 2007
The global smallpox program is generally presented as the brainchild of a handful of actors from the WHO headquarters in Geneva and at the agency's regional offices.
Basu, R. N   +33 more
core   +2 more sources

Rethinking Smallpox [PDF]

open access: yesClinical Infectious Diseases, 2004
The potential consequences of a competently executed smallpox attack have not been adequately considered by policy makers. The possibility of release of an aerosolized and/or bioengineered virus must be anticipated and planned for. The transmission and infectivity of variola virus are examined.
Martin M, Weiss   +3 more
openaire   +2 more sources

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